| 郭卫平,刘燕,王执民,张洪新,曹伟,刘毅勇,樊爱琳.兔肝Vx-2移植癌改良模型的建立[J].中国医学影像技术,2002,18(5):397~399 |
| 兔肝Vx-2移植癌改良模型的建立 |
| The Builder of Retrofit Model of Vx-2 Carcinoma in Rabbit Liver |
| 投稿时间：2001-10-20 |
| DOI： |
| 中文关键词: 兔Vx-2 肝癌 模型 |
| 英文关键词:Rabbit Vx-2 Liver carcinoma Model |
| 基金项目:全军"十五"医学青年基金(01Q124)、第四军医大学科技创新工程(CX99A016)及唐都医院科技苗子基金(2000-07)资助。 |
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| 中文摘要: |
| 目的 建立稳定的兔Vx-2移植性肝癌模型,探讨不同植瘤方式的成功率。方法 将60只新西兰白兔随机分3组,每组20只。观察:①不同方式的成活率;②B超监测肿瘤生长,并计算肿瘤生长率;③瘤组织形态特征。结果 ①改良组植瘤成活率最高(P<0.05),瘤体呈指数性生长;②该瘤在肝组织中呈浸润式生长,其性状与移植于兔其他部位的Vx-2鳞状细胞癌特征相似。结论 成功建立了兔Vx-2移植性肝癌模型,瘤组织块种植方式成功率明显高于其他方法。 |
| 英文摘要: |
| Objective To establish suitable metastatic rabbit Vx-2 liver tumor model for experimental study and to probe the success rate of different tumor transplanted methods.Methods Sixty male New Zealand white rabbits were divided into 3 groups at random, 20 in each group, then to observe:①The success rate of implanted tumor. ②The observation of growth of tumor by ultrasonograpy and calculate the growth rate of tumor. ③The biological features of tumor.Results ①The success rate was the highest in retrofit group (P<0.05). The tumor grew as exponential curve. ②Tumor growth was infiltrated into the normal liver tissue, which had the similar biological features of squamous cell carcinoma that transplanted in other sites of rabbits.Conclusion It is successful to set up retrofit metastatic rabbit Vx-2 liver carcinoma model,the success rate of method that tissue mass of the tumor transplanted is obviously higher than the other two methods. |
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