| 黄国佑,李小成,熊杜.血管内超声评估不同中医证型冠心病动脉粥样硬化斑块特征[J].中国医学影像技术,2024,40(1):51~54 |
| 血管内超声评估不同中医证型冠心病动脉粥样硬化斑块特征 |
| Intravenous ultrasound for evaluating atherosclerotic plaque characteristics of different type traditional Chinese medicine syndrome of coronary heart disease |
| 投稿时间：2023-07-05 修订日期：2023-11-01 |
| DOI：10.13929/j.issn.1003-3289.2024.01.010 |
| 中文关键词: 冠心病 医学,中国传统 超声检查 辨证论治 |
| 英文关键词:coronary disease medicine, Chinese traditional ultrasonography treatment based on syndrome differentiation |
| 基金项目:浙江省医学会临床科研基金项目（成都地奥心血管领域科研专项）（2021ZYC-A216）。 |
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| 中文摘要: |
| 目的 基于血管内超声（IVUS）观察不同中医证型冠心病（CHD）动脉粥样硬化斑块特征。方法 回顾性分析116例CHD患者，根据中医辨证分为气虚血瘀证（n=33）、痰浊阻滞证（n=42）与痰瘀互结证（n=41），比较不同证型CHD患者病变血管及斑块IVUS特征。结果 气虚血瘀证CHD脂质池面积、血管外弹力膜面积、重构指数、斑块偏心性指数均大于痰浊阻滞证 及痰瘀互结证（P均<0.05）；气虚血瘀证斑块内纤维脂质成分比例大于痰瘀互结证（P<0.05）；痰浊阻滞证脂质池面积、血管外弹力膜面积、斑块偏心性指数均小于、而斑块内坏死成分比例大于痰瘀互结证（P均<0.05）。结论 不同证型CHD动脉粥样硬化斑块特征存在一定差异，以气虚血瘀证斑块稳定性最差。 |
| 英文摘要: |
| Objective To observe characteristics of atherosclerotic plaque of coronary heart disease (CHD) with different traditional Chinese medicine (TCM) syndrome type based on intravenous ultrasound (IVUS). Methods Data of 116 CHD patients were retrospectively analyzed. The patients were divided into syndrome of blood stasis due to qi deficiency (n=33), syndrome of blockade of phlegm-turbidity (n=42) as well as syndrome of intermin-gled phlegm and blood stasis (n=41) according to TCM syndrome differentiation. IVUS was performed to compare lesion vessel and plaque characteristics among different syndromic types of CHD. Results The lipid pool area, extravascular elastic membrane area, remodeling index, plaque eccentricity index of CHD with syndrome of blood stasis due to qi deficiency were all larger than those of syndrome of blockade of phlegm-turbidity as well as syndrome of intermin-gled phlegm and blood stasis (all P<0.05). The proportion of fibrous-fatty within plaques of syndrome of blood stasis due to qi deficiency was bigger than that of syndrome of intermin-gled phlegm and blood stasis (P<0.05). The lipid pool area, extravascular elastic membrane area and plaque eccentricity index of CHD of syndrome of blockade of phlegm-turbidity were smaller than, while the proportion of necrotic core within plaques was bigger than those of syndrome of intermin-gled phlegm and blood stasis (all P<0.05). Conclusion Atherosclerotic plaque characteristics in CHD with different TCM syndrome types were different, and the plaque stability of syndrome of blood stasis due to qi deficiency was the worst. |
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