| 武史惠,邓伟,张英霞.不可逆电穿孔技术治疗恶性肿瘤研究进展[J].中国医学影像技术,2024,40(6):928~931 |
| 不可逆电穿孔技术治疗恶性肿瘤研究进展 |
| Research progresses in irreversible electroporation for treatment of malignant tumors |
| 投稿时间：2023-12-23 修订日期：2024-02-22 |
| DOI：10.13929/j.issn.1003-3289.2024.06.027 |
| 中文关键词: 不可逆电穿孔疗法 消融技术 |
| 英文关键词:irreversible electroporation therapy ablation techniques |
| 基金项目: |
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| 中文摘要: |
| 不可逆电穿孔(IRE)技术通过施加电场使细胞发生凋亡而不产生热效应、不损伤脉管结构,与化学治疗和/或免疫疗法联合使用时疗效更佳,是治疗恶性肿瘤的新手段。本文就IRE技术原理及其治疗恶性肿瘤研究进展进行综述。 |
| 英文摘要: |
| Irreversible electroporation (IRE) technology may induce cell apoptosis without generating thermal effect nor vascular structure injuries through electric fields, which has better therapeutic effect when combining with chemotherapy and/or immunotherapy, hence becoming a new option of treating malignant tumors. The mechanisms of IRE and relative research progresses for treating malignant tumors were reviewed in this article. |
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