刘建宪,王振松,王鑫,田宁,陈鹏,于丹,杨燕兴,程传力,邹超,甘洁.基于5.0T MRI定量肝脏质子密度脂肪分数[J].中国医学影像技术,2024,40(5):671~676
基于5.0T MRI定量肝脏质子密度脂肪分数
5.0T MRI for quantifying proton density fat fraction of liver
投稿时间:2024-01-11  修订日期:2024-03-10
DOI:10.13929/j.issn.1003-3289.2024.05.008
中文关键词:    脂肪组织  磁共振成像  脂肪分数  前瞻性研究
英文关键词:liver  adipose tissue  magnetic resonance imaging  fat fraction  prospective studies
基金项目:山东省医药卫生科技项目(202209010957)。
作者单位E-mail
刘建宪 山东大学附属山东省立第三医院影像中心, 山东 济南 250032  
王振松 山东大学附属山东省立第三医院影像中心, 山东 济南 250032  
王鑫 山东大学附属山东省立第三医院影像中心, 山东 济南 250032  
田宁 山东大学附属山东省立第三医院影像中心, 山东 济南 250032  
陈鹏 山东大学附属山东省立第三医院影像中心, 山东 济南 250032  
于丹 北京联影智能影像技术研究院, 北京 100094  
杨燕兴 上海联影医疗科技股份有限公司, 上海 201807  
程传力 深圳先进技术研究院劳特伯生物医学成像研究中心, 广东 深圳 518055  
邹超 深圳先进技术研究院劳特伯生物医学成像研究中心, 广东 深圳 518055  
甘洁 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 ganjie000@sina.com 
摘要点击次数: 129
全文下载次数: 136
中文摘要:
      目的 观察5.0T MRI用于定量肝脏质子密度脂肪分数(PDFF)的价值。方法 前瞻性对30名受试者分别行5.0T、3.0T、1.5T 肝脏化学位移编码(CSE)MR扫描,测量CSE-PDFF;之后行5.0T、1.5T MR波谱(MRS),测量MRS-PDFF。分析不同方法所测肝脏PDFF的一致性,评估5.0T MRI定量肝脏PDFF的价值。结果 以不同场强MR设备所测肝脏CSE-PDFF总体一致性良好(ICC均>0.75,P均<0.001);基于5.0T MR与3.0T、1.5T MR所测肝脏CSE-PDFF的一致性均好(ICC=0.989、0.992,P均<0.001)。基于5.0T MR所测CSE-PDFF与5.0T、1.5T MR所测MRS-PDFF一致性均好(ICC均>0.75,P均<0.001);其中,5.0T MR所测CSE-PDFF与MRS-PDFF一致性好(ICC=0.988,P<0.001),5.0T MR所测CSE-PDFF与1.5T MR所测MRS-PDFF一致性好(ICC=0.978,P<0.001)。结论 5.0T MRI对定量肝脏PDFF具有较高价值。
英文摘要:
      Objective To observe the value of 5.0T MRI for quantifying proton density fat fraction (PDFF) of liver. Methods Liver chemical shift encoded (CSE) MR scanning were prospectively performed using 5.0T, 3.0T and 1.5T scanner in 30 volunteers, respectively, and CSE-PDFF were measured. Then MR spectroscopy (MRS) were performed using 5.0T and 1.5T scanner, respectively, and MRS-PDFF were also measured. The consistency of liver PDFF measured on different images was observed, and the value of 5.0T MRI for liver PDFF was analyzed. Results The overall consistencies of liver CSE-PDFF measured with 5.0T, 3.0T and 1.5T MR scanner were all good (all ICC>0.75, all P<0.001). The consistency of liver CSE-PDFF based on 5.0T and 3.0T, 1.5T MR scanner were both good (ICC=0.989, 0.992, both P<0.001). The overall consistencies of CSE-PDFF based on 5.0T MR and MRS-PDFF based on 5.0T and 1.5T MR were both good (both ICC>0.75, both P<0.001). CSE-PDFF had good consistency with MRS-PDFF based on same 5.0T MR scanner (ICC=0.988, P<0.001), and CSE-PDFF based on 5.0T had good consistency with MRS-PDFF based on 1.5T MR scanner (ICC=0.978, P<0.001). Conclusion 5.0T MRI had high value for quantifying liver PDFF.
查看全文  查看/发表评论  下载PDF阅读器