| 王彦清,聂芳,王陇利,谭玉婷,朱阳阳.二维超声联合声触诊组织成像定量技术诊断唾液腺干燥综合征[J].中国医学影像技术,2021,37(12):1819~1823 |
| 二维超声联合声触诊组织成像定量技术诊断唾液腺干燥综合征 |
| Two-dimensional ultrasound combined with virtual touch tissue imaging quantification technique for diagnosing Sjögren syndrome of salivary glands |
| 投稿时间：2020-07-23 修订日期：2021-09-24 |
| DOI：10.13929/j.issn.1003-3289.2021.12.015 |
| 中文关键词: 干燥综合征 涎腺 超声检查 声触诊组织成像量化 |
| 英文关键词:Sjögren's syndrome salivary glands ultrasonography virtual touch tissue imaging quantification |
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| 中文摘要: |
| 目的 观察二维超声联合声触诊组织成像定量（VTIQ）技术诊断唾液腺干燥综合征（SS）的价值。方法 收集43例SS患者（SS组）和60例非SS患者（对照组），观察并对比其唾液腺病灶二维超声评分及剪切波速度（SWV），绘制受试者工作特征（ROC）曲线，评估二维超声评分、VTIQ及二者联合诊断唾液腺SS的效能。结果 SS组唾液腺二维超声评分及唾液腺SWV均明显高于对照组（P均<0.01）。以2.12、2.38 m/s为唾液腺（腮腺、下颌下腺）SWV最佳截断值，其诊断唾液腺SS的敏感度、特异度、约登指数和曲线下面积（AUC）分别为83.70%、88.30%、0.72和0.90；以二维超声评分2分为最佳截断值，其诊断唾液腺SS的敏感度、特异度、约登指数和AUC分别为76.70%、90.00%、0.67和0.91；以二维超声评分为1分且唾液腺SWV=2.12、2.38 m/s为最佳截断值，联合诊断唾液腺SS的敏感度、特异度、约登指数和AUC分别为95.30%、60.00%、0.55和0.78。结论 二维超声联合VTIQ技术有助于诊断唾液腺SS。 |
| 英文摘要: |
| Objective To observe the value of two-dimensional ultrasound combined with virtual touch tissue imaging quantification (VTIQ) technique for diagnosing Sjögren syndrome (SS) of salivary glands. Methods Totally 43 patients with SS (SS group) and 60 patients without SS (control group) were enrolled. Two-dimensional ultrasound scoring and shear wave velocity (SWV) of salivary gland lesions were performed and compared between groups. Receiver operating characteristic (ROC) curves were drawn, and the efficacies of two-dimensional ultrasound scoring, VTIQ and their combination for diagnosing SS of salivary glands were evaluated. Results Two-dimensional ultrasound scores and SWV of salivary glands (parotid gland and submandibular gland) of SS group were significantly higher than those of control group (all P<0.01). Taken 2.12 m/s and 2.38 m/s as the best cut-off value of SWV of parotid gland and submandibular gland, the sensitivity, specificity, Youden index and area under the curve (AUC) for diagnosing SS of salivary gland was 83.70%, 88.30%, 0.72 and 0.90, respectively. Taken 2 points as the best cut-off value of two-dimensional ultrasound score, the sensitivity, specificity, Youden index and AUC was 76.70%, 90.00%, 0.67 and 0.91, respectively. Taken 1 point, 2.12 m/s and 2.38 m/s as the best cut-off values of two-dimensional ultrasound score and SWV of parotid gland and submandibular gland, the sensitivity, specificity, Youden index and AUC was 95.30%, 60.00%, 0.55 and 0.78, respectively. Conclusion Two-dimensional ultrasound combined with VTIQ technique was helpful for diagnosing SS of salivary glands. |
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