李岩,王清国,耿斌,秦金霞,帖永新,常凤玲,冯俊,翟慧萍.母体抗SSA/SSB抗体阳性胎儿完全性房室传导阻滞超声表现[J].中国医学影像技术,2021,37(7):1034~1038
母体抗SSA/SSB抗体阳性胎儿完全性房室传导阻滞超声表现
Ultrasonic manifestations of complete atrioventricular block in fetuses with positive maternal anti-SSA/SSB antibodies
投稿时间:2020-08-27  修订日期:2021-05-09
DOI:10.13929/j.issn.1003-3289.2021.07.016
中文关键词:  胎儿  房室传导阻滞  抗SSA抗体  抗SSB抗体  超声检查
英文关键词:fetus  atrioventricular block  anti-SSA antibody  anti-SSB antibody  ultrasonography
基金项目:2019年度河南省医学科技攻关计划联合共建项目(LHGJ20191324)。
作者单位E-mail
李岩 新乡市中心医院超声一科, 河南 新乡 453000 xinxiangliyan@sina.com 
王清国 滨州市人民医院超声科, 山东 滨州 256603  
耿斌 首都医科大学附属北京安贞医院小儿心脏中心, 北京 100029  
秦金霞 新乡市中心医院超声一科, 河南 新乡 453000  
帖永新 新乡市中心医院超声一科, 河南 新乡 453000  
常凤玲 新乡市中心医院超声一科, 河南 新乡 453000  
冯俊 新乡市中心医院超声一科, 河南 新乡 453000  
翟慧萍 新乡市第二人民医院超声科, 河南 新乡 453000  
摘要点击次数: 247
全文下载次数: 148
中文摘要:
      目的 观察母体抗SSA/SSB抗体阳性胎儿完全性房室传导阻滞(CAVB)超声表现。方法 以二维、M型及多普勒超声技术观察7胎母体抗SSA/SSB抗体阳性CAVB胎儿心脏,获取二尖瓣、左心室流入道及流出道、脐动脉(UA)、静脉导管(DV)及大脑中动脉(MCA)血流频谱。结果 7名孕妇抗SSA抗体、抗Ro52抗体均呈阳性,其中4名抗SSB抗体呈阳性。7胎均见房室分离,心房律正常而心室律缓慢,二尖瓣、UA、DV及MCA血流异常;其中4胎心房壁、房间隔、二尖瓣环或腱索回声增强。7胎均未合并其他心内外结构畸形。结论 母体抗SSA/SSB抗体阳性可致胎儿发生CAVB;超声观察胎儿心脏及血流动力学变化有利于判断胎儿预后。
英文摘要:
      Objective To observe the ultrasonic manifestations of complete atrioventricular block (CAVB) in fetuses with positive maternal anti-SSA/SSB antibodies. Methods Seven CAVB fetuses with positive maternal anti-SSA/SSB antibodies were enrolled. Two dimensional, M-type and Doppler ultrasonography were used to observe the fetal ultrasonic manifestations, and the blood flow spectrums of the mitral valve, left ventricular inflow and outflow tract, umbilical artery (UA), venous catheter (DV) and middle cerebral artery (MCA) were obtained. Results All 7 pregnant women were positive for anti-SSA and anti-Ro52 antibodies, and 4 of them were positive for anti-SSB antibody. Ultrasound showed enhanced echoes in atrial wall, interatrial septum, mitral annulus or chordae tendineae in 4 fetuses. All 7 fetuses had atrioventricular dissociation, with normal atrial rhythms, slow ventricular rhythms and abnormal blood flow of mitral valve, UA, DV and MCA. No other internal and external cardiac malformations was detected in 7 fetuses. Conclusion Positive maternal anti-SSA/SSB antibodies could lead to fetal CAVB. Detecting the changes of fetal heart and hemodynamics by ultrasound was helpful to evaluation on prognosis of fetus.
查看全文  查看/发表评论  下载PDF阅读器