| 郭杨钰,谭利华,姜孟春,谢幸芷,邓淇予,曾牧.心血管磁共振组织追踪技术评价心肌淀粉样变性与其他左心室肥厚疾病心肌应变差异[J].中国医学影像技术,2020,36(3):382~386 |
| 心血管磁共振组织追踪技术评价心肌淀粉样变性与其他左心室肥厚疾病心肌应变差异 |
| Evaluation of myocardial strain differences of cardiac amyloidosis and other left ventricular hypertrophy diseases with cardiovascular magnetic resonance tissue tracking technique |
| 投稿时间：2019-04-15 修订日期：2020-02-11 |
| DOI：10.13929/j.issn.1003-3289.2020.03.015 |
| 中文关键词: 心肌病,肥厚性 心室功能,左 磁共振成像 |
| 英文关键词:cardiomyopathy,hypertrophic ventricular function,left magnetic resonance imaging |
| 基金项目:国家科学基金青年科学基金项目（81701660）。 |
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| 中文摘要: |
| 目的 探讨心血管磁共振组织追踪技术（CMR-TT）评估心肌淀粉样变（CA）与其他左心室肥厚疾病的左心室心肌应变差异的可行性。方法 对30例CA（CA组）、30例肥厚型心肌病（HCM组）、29例高血压致左心室肥厚（HLVH组）患者及30名健康人（NC组）行CMRI，经后处理得到左心室整体和各水平（基底部、中间部和心尖部）3D径向应变（RS）、周向应变（CS）、纵向应变（LS）、左心室室壁厚度及心功能参数，分析各参数的组间差异。结果 NC组左心室整体及各节段室壁厚度小于其他3组（P均<0.05）。除每搏输出量指数外，4组间其他心功能参数差异均有统计学意义（P均<0.05）。4组间左心室整体及各节段心肌应变、LS梯度差和心尖相对LS（RAS LS）差异均有统计学意义。4组间左心室基底到心尖LS递增，CA组最为显著。CA组基底到心尖LS梯度差[（-5.18±3.33）%]大于HCM组、HLVH组及NC组[（-3.12±2.47）%、（-2.71±1.81）%及（-3.19±2.21）%，P均<0.05]，左心室RAS LS[0.88（0.78，1.18）]大于HCM组、HLVH组及NC组[0.62（0.56，0.72）、0.65（0.59，0.82）及0.60（0.55，0.65），P均<0.05]。结论 采用CMR-TT技术可定量评估CA和其他左心室肥厚疾病的左心室心肌应变。左心室基底到心尖LS梯度差与RAS LS可为鉴别CA与其他左心室肥厚相关疾病提供依据。 |
| 英文摘要: |
| Objective To evaluate myocardial strain of cardial amyloidosis (CA) and other left ventricular hypertrophy diseases using cardiovascular magnetic resonance tissue tracking (CMR-TT), and to analyze the differences of myocardial strain among CA, hypertrophic cardiomyopathy(HCM) and hypertension caused left ventricular hypertrophy (HLVH). Methods Totally 30 patients with CA (CA group), 30 with HCM (HCM group), 29 with HLVH and 30 normal controls (NC group) underwent CMRI. Then 3D radial strain (RS), circumferential strain (CS), longitudinal strain (LS), myocardial thickness of global left ventricular and each myocardial segment (basal, middle and apical) and cardiac function parameters were obtained with post-processing software, and the differences of parameters of 4 groups were analyzed.Results The myocardial thicknesses of global left ventricular and every myocardial segment in NC group were less than that of the rest 3 groups (all P<0.05). Except for stroke volume index, there were statistically differences of cardiac function indexes, also of left ventricular global and segmental myocardial strain, LS gradient and relative apical sparing of longitudinal strain (RAS LS) among all 4 groups (all P<0.05). LS of left ventricular base to apex all increased in all 4 groups, and the most significant changes were detected in CA group. LS gradient from left ventricular base to apex of CA group ([-5.18±3.33]%) was greater than that of HCM group, HLVH group and NC group ([-3.12±2.47]%,[-2.71±1.81]% and[-3.19±2.21]%, all P<0.05). RAS LS of CA group ([0.88(0.78, 1.18)]) was greater than that of HCM group, HLVH group and NC group (0.62[0.56, 0.72], 0.65[0.59, 0.82] and 0.60[0.55, 0.65], all P<0.05).Conclusion CMR-TT can be used to quantitatively evaluate left ventricular myocardial strain of CA and other left ventricular hypertrophy diseases. LS gradient from left ventricular base to apex and RAS LS of CA can provide evidences for identifying CA and other left ventricular hypertrophy diseases. |
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