陈国强,苏福,王卫星,马超.18F-FDG PET/CT联合薄层螺旋CT三维重建诊断孤立性肺结节[J].中国医学影像技术,2020,36(1):86~90
18F-FDG PET/CT联合薄层螺旋CT三维重建诊断孤立性肺结节
18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice helical CT in diagnosis of solitary pulmonary nodules
投稿时间:2019-05-27  修订日期:2019-11-29
DOI:10.13929/j.issn.1003-3289.2020.01.024
中文关键词:  孤立性肺结节  正电子发射断层显像术  薄层扫描  三维重建
英文关键词:solitary pulmonary nodules  positron-emission tomography  thin-slice scanning  three-dimensional reconstruction
基金项目:福建省卫计委青年科研项目(2015-2-46)、厦门市科技局科技计划项目(3502Z20164021)。
作者单位E-mail
陈国强 厦门大学附属中山医院核医学科, 福建 厦门 361004  
苏福 厦门大学附属中山医院核医学科, 福建 厦门 361004  
王卫星 厦门大学附属中山医院核医学科, 福建 厦门 361004  
马超 厦门大学附属中山医院核医学科, 福建 厦门 361004 machaoready@163.com 
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中文摘要:
      目的 观察18F-FDG PET/CT联合薄层螺旋CT三维重建对孤立性肺结节(SPN)的诊断价值。方法 对139例SPN患者采用18F-FDG PET/CT常规扫描后行肺部薄层螺旋CT扫描和三维重建,对比分析18F-FDG PET/CT联合薄层螺旋CT三维重建和单独诊断SPN的准确率。结果 139例SPN,经病理证实恶性83例、良性48例,8例经临床抗感染治疗病灶变小或消失而诊断为良性SPN。PET/CT联合薄层CT三维重建诊断SPN的灵敏度85.71%(72/84)、特异度78.18%(43/55),诊断符合率82.73%(115/139),均高于单独18F-FDG PET/CT[64.29%(54/84)、54.55%(30/55)及60.43%(84/13)]。结论 联合CT三维重建能明显提高18F-FDG PET/CT诊断SPN的准确率。
英文摘要:
      Objective To explore the value of 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of solitary pulmonary nodules (SPN). Methods A total of 139 patients with SPN were selected. After routine 18F-FDG PET/CT scanning, thin-slice spiral CT scanning and three-dimensional reconstruction were performed. The accuracy of single 18F-FDG PET/CT and 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT in diagnosis of SPN were recorded and compared. Results Totally 139 SPN were pathologically confirmed after operation or puncture, including 83 malignant and 48 benign ones. SPN in 8 patients became small or disappeared after clinical anti-inflammatory treatment, and thus were diagnosed as benign ones. The sensitivity, specificity and coincidence rate of combined diagnosis of SPN nodules was 85.71% (72/84), 78.18% (43/55) and 82.73% (115/139), respectively, all higher than of single 18F-FDG PET/CT (64.29%[54/84], 54.55%[30/55] and 60.43%[84/139], respectively). Conclusion 18F-FDG PET/CT combined with three-dimensional reconstruction of thin-slice spiral CT can significantly improve the accuracy for diagnosing SPN.
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