| 张子田,李松柏,韩向军,王洋,王嘉奇.离体胆结石成分能谱CT分析[J].中国医学影像技术,2019,35(9):1404~1408 |
| 离体胆结石成分能谱CT分析 |
| In vitro analysis of gallstone composition with spectral CT |
| 投稿时间：2018-10-23 修订日期：2019-04-02 |
| DOI：10.13929/j.1003-3289.201810124 |
| 中文关键词: 胆结石 体层摄影术,X线计算机 双能量成像 |
| 英文关键词:gallstone tomography, X-ray computed dual energy imaging |
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| 摘要点击次数: 1992 |
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| 中文摘要: |
| 目的 探讨能谱CT各参数鉴别纯胆固醇及非纯胆固醇结石的价值。方法 采用能谱CT扫描离体胆结石，以红外光谱确定结石成分并分组，并于轴位、冠状位及矢状位结石最大层面勾画ROI，获得结石的能谱曲线及能谱CT测量参数[CT值、斜率、有效原子序数（Zeff）、钙水比值（CWR）]，以Mann-Whitney U检验比较组间和亚组间参数的差异。利用ROC曲线获得各参数鉴别纯胆固醇及非纯胆固醇结石组的阈值，计算敏感度、特异度、阳性预测值和阴性预测值。结果 纯胆固醇及非纯胆固醇结石组各能谱CT参数差异均有统计学意义（P均<0.01）。各能谱参数鉴别诊断纯胆固醇与非纯胆固醇结石的AUC差异均无统计学意义（P均>0.05）。结论 各能谱参数鉴别纯胆固醇与非纯胆固醇结石效能均较好；不同成分胆结石能谱曲线存在差异。 |
| 英文摘要: |
| Objective To explore the value of spectral CT in differentiating pure and impure cholesterol stones. Methods Spectral CT was used to scan in vitro gallstones, and infrared spectroscopy spectrum was used to observe the composition and classification of gallstones. ROIs were outlined in the axial, coronal and sagittal maximum planes of gallstones. Spectral CT indexes, including spectral curves, CT value, CT slope, effective atomic number (Zeff) and calcium-water ratio (CWR)) of the stones were acquired. Mann-Whitney U test was used to analyze the differences of parameters among different gallstone groups and subgroups. ROC curve was used to determine the diagnostic threshold, sensitivity, specificity, positive predictive value and negative predictive value of pure and impure cholesterol stone group. Results There were significant differences of CT parameters between pure and impure cholesterol stone groups (all P<0.01). The AUC of the different parameters in differetical the pure and impure cholesterol stone had no statistical difference (all P>0.05). Conclusion The parameters of pure and impure cholesterol stones have good diagnostic efficacies. There are differences of energy spectrum curves of gallstones with different compositions. |
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