| 杨智,李睿,付兵,李春平,杨帆,王文斌.心脏MR T2* mapping技术定量评价2型糖尿病患者左心室心肌改变[J].中国医学影像技术,2019,35(2):200~203 |
| 心脏MR T2* mapping技术定量评价2型糖尿病患者左心室心肌改变 |
| Cardiac MR T2* mapping in quantitative evaluation of left ventricle myocardium in patients with type 2 diabetes mellitus |
| 投稿时间：2018-03-05 修订日期：2018-08-25 |
| DOI：10.13929/j.1003-3289.201803029 |
| 中文关键词: 糖尿病,2型 心室功能,左 磁共振成像 |
| 英文关键词:diabetes mellitus, type 2 ventricular function, left magnetic resonance imaging |
| 基金项目:四川省医学科研青年创新课题计划（Q15023）、四川省医学会科研课题计划（S15013）。 |
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| 中文摘要: |
| 目的 探讨心脏MR T2* mapping技术定量评价2型糖尿病（T2DM）患者心肌改变的临床价值。方法 对54例T2DM患者（T2DM组）及43名健康志愿者（正常对照组）采用T2* mapping技术行心脏MR检查。测量并比较2组间左心室各节段心肌及各支冠状动脉供血区心肌T2*值的差异。结果 T2DM组左心室第6、15、16节段T2*值低于正常对照组（P均<0.05），2组间其余各节段心肌T2*值差异均无统计学意义（P均>0.05）。T2DM组冠状动脉左回旋支（LCX）供血区心肌T2*值低于正常对照组（P=0.035），2组间左前降支（LAD）及右冠状动脉（RCA）供血区心肌T2*值差异均无统计学意义（P均>0.05）。结论 T2* mapping技术可用于定量评价T2DM患者左心室心肌改变，有助于早期发现糖尿病心肌病。 |
| 英文摘要: |
| Objective To explore the clinical value of cardiac magnetic resonance (CMR) T2* mapping in quantitative evaluation of left ventricle myocardium changes in patients with type 2 diabetes mellitus (T2DM). Methods A total of 54 patients with T2DM (T2DM group) and 43 healthy volunteers (control group) underwent CMR scanning. T2* values of different left myocardial and coronary artery blood supply areas were measured and compared between the two groups. Results T2* values of the 6th, 15th and 16th left myocardial segments in T2DM group were lower than those in control group (all P<0.05). There was no statistic difference of T2* values of the other left myocardial segments between the two groups (all P>0.05). T2* values of myocardium in left circumflex artery (LCX) supply area in T2DM group were lower than those in control group (P=0.035), while no statistic difference of left anterior descending coronary artery (LAD) nor right coronary artery (RCA) supply areas T2* values was found between the two groups (all P>0.05). Conclusion T2* mapping technique can be used to quantitatively evaluate myocardial changes of left ventricle in patients with T2DM, which are helpful to early detection of diabetic cardiomyopathy. |
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