陈烨颖,潘小环,关玉宝,杨新官,刘海平,陈萍.18F-FDG PET/CT诊断复发性多软骨炎[J].中国医学影像技术,2019,35(1):138~142
18F-FDG PET/CT诊断复发性多软骨炎
18F-FDG PET/CT in diagnosis of relapsing polychondritis
投稿时间:2018-05-07  修订日期:2018-09-07
DOI:10.13929/j.1003-3289.201805033
中文关键词:  多软骨炎,复发性  正电子发射型体层摄影术  氟脱氧葡萄糖F18
英文关键词:polychondritis, relapsing  positron-emission tomography  fluorodeoxyglucose F 18
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作者单位E-mail
陈烨颖 广州医科大学附属第一医院放射科, 广东 广州 510120  
潘小环 广州医科大学附属第一医院放射科, 广东 广州 510120  
关玉宝 广州医科大学附属第一医院放射科, 广东 广州 510120 yubaoguan@163.com 
杨新官 广州医科大学附属第一医院放射科, 广东 广州 510120  
刘海平 广州医科大学附属第一医院核医学科, 广东 广州 510120  
陈萍 广州医科大学附属第一医院核医学科, 广东 广州 510120  
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中文摘要:
      目的 探讨18F-FDG PET/CT对复发性多软骨炎(RP)的诊断价值。方法 回顾性分析28例RP患者(RP组)及28名健康志愿者(对照组)的18 F-FDG PET/CT表现,观察病灶部位、形态、边界及密度,计算病灶最大标准摄取值(SUVmax)。绘制ROC曲线,评价病灶SUVmax对RP的诊断效能。结果 28例RP患者中24例见气管及支气管密度增高、边界模糊及管壁增厚;4例见喉软骨密度增高、管壁水肿及增厚,边界模糊。共91个病灶,均位于鼻软骨、双侧耳廓软骨、肋软骨、喉软骨、气管及支气管软骨5个部位,各部位病灶SUVmax均高于对照组相同部位(P均<0.01)。ROC曲线结果示肋软骨、喉软骨、气管及主支气管软骨、双侧耳廓软骨SUVmax对RP的诊断价值均较高(AUC均>0.9),鼻软骨诊断价值中等(AUC=0.71)。结论 RP患者18F-FDG PET/CT表现有一定特异性,可同时显示多部位病灶,有助于RP诊断。
英文摘要:
      Objective To explore the value of 18F-FDG PET/CT in diagnosis of relapsing polychondritis (RP). Methods 18F-FDG PET/CT imaging features of 28 patients of RP (RP group) and 28 healthy volunteers (control group) were retrospectively analyzed. The lesions' location, shape, margins, density and the maximum standardized uptake (SUVmax) were analyzed. ROC curve was used to evaluate the efficacy of SUVmax of lesions in diagnosis of RP. Results In all 28 RP patients, increased density, blurred boundary and thickened wall of trachea and bronchus were found in 24 cases. Four cases showed increased density and fuzzy boundary, as well as edema and thickening in larynx cartilages. Totally 91 lesions were found with PET/CT, located in the nasal cartilages, bilateral auricular cartilages, costal cartilages, laryngeal cartilages, trachea and bronchial cartilages, respectively. SUVmax of lesions on each site in RP group was higher than those in control group (all P<0.01). ROC results showed SUVmax of costal cartilages, laryngeal cartilages, trachea and main bronchial cartilages, bilateral auricular cartilages had high diagnostic value for diagnosing RP (all AUC>0.90), while SUVmax of nasal cartilages had a moderate diagnostic value (AUC=0.71). Conclusion 18F-FDG PET/CT manifestations of RP have some characteristics, and can display multiple lesions simultaneously, therefore being helpful to diagnosis of RP.
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