| 应倩,武育蓉,陈笋,孙锟.时间-空间关联成像技术评估圆锥动脉干畸形胎儿心功能[J].中国医学影像技术,2018,34(9):1284~1288 |
| 时间-空间关联成像技术评估圆锥动脉干畸形胎儿心功能 |
| Evaluation on cardiac function in fetus with conotruncal defects using spatiotemporal image correlation technique |
| 投稿时间：2017-07-18 修订日期：2018-05-29 |
| DOI：10.13929/j.1003-3289.201707084 |
| 中文关键词: 时间-空间关联成像技术 圆锥动脉干畸形 胎儿 心功能 |
| 英文关键词:Spatiotemporal image correlation Conotruncal defect Fetus Cardiac function |
| 基金项目:上海市公共卫生体系建设三年行动计划（GWIV-23）、申康市级医院新兴前沿技术联合攻关项目（SHDC12015102）。 |
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| 中文摘要: |
| 目的 应用时间-空间关联成像（STIC）技术评价圆锥动脉干畸形（CTD）胎儿心功能。方法 选取经胎儿超声心动图诊断的39胎CTD胎儿（CTD组）和39胎正常胎儿（对照组）。采用STIC技术评估2组胎儿的心功能，包括肺动脉（PA）内径、左心室舒张末期内径（LVDD）和右心室舒张末期内径（RVDD）、左心室收缩末期内径（LVDS）、右心室收缩末期内径（RVDS）、缩短分数（FS）、左心室舒张末期容积（LVEDV）、右心室舒张末期容积（RVEDV）、左心室收缩末期容积（LVESV）、右心室收缩末期容积（RVESV）、每搏输出量（SV）和射血分数（EF）等指标，并比较2组间的差异。结果 与对照组比较，CTD组胎儿PA内径及PA/AO均减小（P均<0.001），LVDD、LVDS、RVDD、RVDS、LVEDV、LVESV、RVEDV及RVESV差异均无统计学意义（P均> 0.05），左、右心室FS、EF及SV均降低（P均<0.05），LVDD／RVDD明显升高（P均<0.01）。CTD组中，RVEDV高于LVEDV（P < 0.05），左心室SV及EF均低于右心室（P均<0.05）。结论 CTD在产前即可对胎儿心功能造成影响，右心室功能有代偿性增强表现，而右心扩大不明显。 |
| 英文摘要: |
| Objective To evaluate cardiac function of fetuses with conotruncal defect (CTD) using spatio-temporal image correlation. Methods Totally 39 fetuses with CTD confirmed by echocardiography (CTD group) and 39 normal fetuses (control group) were enrolled. STIC was used to evaluate fetal cardiac function, and the parameters were compared between the two groups, including the diameter of pulmonary artery (PA), left ventricular end diastolic diameter (LVDD), right ventricular end diastolic diameter (RVDD), left ventricular end systolic diameter (LVDS), right ventricular end systolic diameter (RVDS), fractional shortening (FS), left ventricular end-diastolic volume (LVEDV) and right ventricular end-diastolic volume (RVEDV), left ventricular end-systolic volume (LVESV) and right ventricular end-systolic volume (RVESV), stroke volume (SV) and ejection fraction (EF). Results Compared with control group, the diameter of PA and PA/AO were smaller in CTD group (both P<0.001), while there was no significant difference of LVDD, LVDS, RVDD, RVDS, LVEDV, LVESV, RVEDV nor RVESV between the two groups (all P > 0.05). FS, EF and SV in CTD group were lower than those in control group (all P<0.05). CTD fetuses had significantly larger RVDD/LVDD (P<0.001). Additionally, RVEDV was higher than LVEDV (P < 0.05), and left ventricular SV and left ventricular EF were lower than right ventricular SV and right ventricular EF in CTD group (all P<0.05). Conclusion CTD may have prenatal impact on fetal cardiac function, which may result increased right ventricle function while enlargement of right ventricle is not obvious. |
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