| 唐世龙,何玲,刘波,周瑜,刘先凡.学龄前儿童三维动脉自旋标记脑血流灌注中的最佳标记后延迟时间[J].中国医学影像技术,2018,34(8):1258~1262 |
| 学龄前儿童三维动脉自旋标记脑血流灌注中的最佳标记后延迟时间 |
| Optimal post label delay time in 3D-arterial spin labeling cerebral perfusion in preschool children |
| 投稿时间：2018-01-12 修订日期：2018-05-17 |
| DOI：10.13929/j.1003-3289.201801077 |
| 中文关键词: 标记后延迟时间 学龄前儿童 动脉自旋标记 颅脑 磁共振成像 |
| 英文关键词:Post label delay time Child, preschool Arterial spin labeling Brain Magnetic resonance imaging |
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| 中文摘要: |
| 目的 探讨标记后延迟时间（PLD）对于学龄前儿童3D-动脉自旋标记（ASL）脑血流灌注图像的影响。方法 收集常规MRI表现正常的250例学龄前儿童患者，根据年龄分为<1个月、1~6个月、>6~12个月、>1~3岁、>3~6岁组，每组50例，行3D-ASL脑灌注MR扫描，PLD分别设置为1 025 ms、1 525 ms和2 025 ms，分析比较3D-ASL灌注图像的主观质量评价、SNR和脑血流量（CBF），其中甲级图像为SNR高、无伪影、脑沟无信号。结果 <1个月组和1~6个月组中，PLD值为1 025 ms时，图像以甲级为主，分别有43例和46例，脑CBF和SNR均高于PLD值为1 525 ms和2 025 ms的图像。> 6~12个月组、> 1~3岁组和 > 3~6岁组中，PLD值为1 525 ms时，图像以甲级为主，分别有43、45和43例，脑CBF值和SNR均高于PLD值为1 025 ms和2 025 ms图像。结论 不同年龄段学龄前儿童3D-ASL脑血流灌注的最佳PLD值不同，≤6个月婴幼儿的最佳PLD值为1 025 ms，对>6个月~6岁儿童PLD值宜选用1 525 ms。 |
| 英文摘要: |
| Objective To explore the impact of post label delay (PLD) time on 3D-arterial spin labeling (ASL) cerebral perfusion imaging in preschool children. Methods Totally 250 preschool children with normal MRI demonstration were enrolled and evenly divided into <1 month, 1-6 months, >6-12 months, >1-3 years, >3-6 years groups according to the age. All children underwent 3D-ASL imaging with PLD time of 1 025 ms, 1 525 ms and 2 025 ms. The image quality, SNR and cerebral blood flow (CBF) were compared and analyzed. Images with high SNR, no artifacts and no signal of brain fissure were regarded as class A. Results In <1 month and 1-6 months groups, when PLD time was 1 025 ms, most images (43 and 46 patients, respectively) were class A, and CBF and SNR were higher than those in images with PLD of 1 525 ms and 2 025 ms. In >6-12 months, >1-3 years and >3-6 years groups, when PLD value was 1 525 ms, most images (43, 45, 43 patients, respectively) were class A, and CBF and SNR were higher than those in images with PLD of 1 025 ms and 2 025 ms. Conclusion Different PLD time of 3D-ASL cerebral perfusion imaging is necessary for different aged preschool children. For ≤ 6 months children, the best PLD time may be 1 025 ms, while for >6 months-6 years old children, the best PLD time may be 1 525 ms. |
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