张杰,陈文娟,孟慧娴,胡原,段星星.儿童郎格罕细胞组织细胞增生症腹部超声表现[J].中国医学影像技术,2018,34(6):884~887
儿童郎格罕细胞组织细胞增生症腹部超声表现
Abdominal ultrasonographic manifestations of Langerhans cells histiocytosis in children
投稿时间:2017-07-27  修订日期:2018-03-04
DOI:10.13929/j.1003-3289.201707135
中文关键词:  儿童  组织细胞增多症,郎格尔汉斯细胞  超声检查
英文关键词:Child  Histiocytosis, Langerhans-cell  Ultrasonography
基金项目:
作者单位E-mail
张杰 湖南省儿童医院超声科, 湖南 长沙 410007  
陈文娟 湖南省儿童医院超声科, 湖南 长沙 410007 270615734@qq.com 
孟慧娴 湖南省儿童医院超声科, 湖南 长沙 410007  
胡原 湖南省儿童医院超声科, 湖南 长沙 410007  
段星星 湖南省儿童医院超声科, 湖南 长沙 410007  
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中文摘要:
      目的 探讨钆塞酸二钠(Gd-EOB-DTPA)增强MRI评估肝功能正常者及肝功能受损患者肝脏储备功能。方法 将99例乙型肝炎肝硬化肝功能异常者分为Child-Pugh A级(Child-Pugh A级组;n=48)、B级(Child-Pugh B级组;n=40)、C级(Child-Pugh C级组;n=11),以21例无慢性肝病肝功能正常者为肝功能正常组(n=21)。行Gd-EOB-DTPA增强MRI,于注射对比剂后3 min、10 min、20 min图像计算全肝及各肝段相对强化程度(RE),比较不同肝功能分组间、各肝段间(S1~S8)肝脏RE的差异。结果 增强后3 min、10 min、20 min,Child-Pugh A级、B级、C级组与肝功能正常组间全肝RE和各肝段RE总体差异均有统计学意义(P均<0.05)。增强后3 min、10 min、20 min,肝功能正常组及Child-Pugh A级组各肝段间RE差异均有统计学意义(P均<0.05),Child-Pugh B级组增强后10 min、20 min和Child-Pugh C级组增强后20 min各肝段间RE差异有统计学意义(P均<0.05)。结论 Gd-EOB-DTPA增强MRI可准确评估全肝及各肝段的功能。
英文摘要:
      Objective To observe the abdominal ultrasonic manifestations of children with Langerhans cells histiocytosis (LCH). Methods Imaging features of histopathologically proved LCH in 28 children were retrospectively analyzed. Results Among 28 cases, multi-system involvement was found in 25 cases, while only liver and bile duct involvement were detected in 3 cases. Different degrees of enlarged liver, inhomogeneous echo of liver parenchyma, scattered or diffuse hypoechoic regions were found in all 28 cases. Uneven thickening and echo enhancement of the bile duct wall, as well as local expansion or stricture of bile duct cavity were found in 13 cases. Splenomegaly was found in 17 cases, swelling of the pancreas was found in 5 cases, varying degrees of ascites were found in 13 cases, and hepatic hilar lymphadenectasis were found in 14 cases. Conclusion There are specific ultrasonographic manifestations of LCH in children, which may be helpful to improving diagnostic accuracy of LCH.
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