| 谢传飞,孙玲玲,吴业君,郭俊辰.急性脑梗死全脑CT灌注成像扫描时间优化[J].中国医学影像技术,2017,33(10):1488~1492 |
| 急性脑梗死全脑CT灌注成像扫描时间优化 |
| Optimizing scanning time of CT perfusion imaging in acute cerebral infarction |
| 投稿时间：2017-03-17 修订日期：2017-07-17 |
| DOI：10.13929/j.1003-3289.201703089 |
| 中文关键词: 脑梗死 体层摄影术,X线计算机 灌注成像 辐射剂量 |
| 英文关键词:Brain infarction Tomography, X-ray computed Perfusion imaging Radiation dosage |
| 基金项目:辽宁省自然科学基金（2013021035）。 |
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| 中文摘要: |
| 目的 探讨缩短扫描时间对急性脑梗死全脑CT灌注（CTP）图像质量和灌注参数值的影响。方法 回顾性分析30例诊断为单侧急性脑梗死患者的全脑CTP资料。按不同扫描时间（56 s、52 s、48 s、44 s、40 s及36 s）分组，对灌注数据进行图像后处理，获得各组上矢状窦灌注时间密度曲线（TDC）、灌注伪彩图和灌注参数值，并记录上矢状窦首次通过时间。结果 与扫描时间56 s组比较，52 s组及48 s组CTP图像质量差异无统计学意义（P均>0.05）。扫描时间52 s组、48 s组、44 s组、40 s组和36 s组CTP图像质量主观评分与上矢状窦首次通过时间呈负相关。与扫描时间56 s组比较，当扫描时间缩短至44 s及以下时，对部分灌注参数值的测量差异有统计学意义（P均<0.05）。结论 适当缩短全脑CTP扫描时间，在保证CTP图像质量和灌注值测量准确性同时，可减少辐射剂量，推荐全脑CTP选择延迟8 s，扫描时间48 s。 |
| 英文摘要: |
| Objective To explore the effect of scanning time on CT perfusion (CTP) imaging quality and the accuracy of parameters in acute stroke patients. Methods CTP data of 30 patients with unilateral acute cerebral infarction were investigated retrospectively. CTP data with scanning times of 56 s, 52 s, 48 s, 44 s, 40 s and 36 s were analyzed for image post-processing, the time density curves (TDCs) of the superior sagittal sinus (SSS), perfusion maps and the parameter values of ROI were obtained, and the first passage time of SSS was recorded. Results Compared with 56 s group, there was no significant difference of the image quality in the scanning time of 52 s group and 48 s group (both P>0.05). The image quality was significantly negatively correlated with the first passage time of SSS in 52 s group, 48 s group, 44 s group, 40 s group and 36 s group. Compared with 56 s group, there were significant differences in partial parameters of ROI when the scanning time was 44 s (all P<0.05). Conclusion Decreasing whole-brain CTP scanning time reasonably can ensure the image quality and the accuracy of parameters and reduce the radiation dose. The whole-brain CTP with delay of 8 s, and scanning time of 48 s are recommended. |
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