| 黎美玲,陆健,曹鹏.动态对比增强MRI在肝脏中的应用与研究进展[J].中国医学影像技术,2017,33(1):149~152 |
| 动态对比增强MRI在肝脏中的应用与研究进展 |
| Application and research progresses of dynamic contrast-enhanced MRI in liver |
| 投稿时间：2016-06-19 修订日期：2016-09-30 |
| DOI：10.13929/j.1003-3289.201606090 |
| 中文关键词: 动态增强 磁共振成像 肝脏 |
| 英文关键词:Dynamic contrast-enhanced Magnetic resonance imaging Liver |
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| 摘要点击次数: 1947 |
| 全文下载次数: 909 |
| 中文摘要: |
| 动态对比增强MRI（DCE-MRI）是一种基于对比剂药物代谢动力学的MR成像方法，可用于观察、分析组织微循环功能状态。肝脏接受双重血供，又受到周围器官运动的影响，因此将DCE-MRI用于肝脏面临更多挑战。但随着技术成熟与研究深入，肝脏DCE-MRI应用研究逐渐开展，主要包括抗血管靶向治疗药物研发、疗效反应监测与预后评估、肿瘤诊断与分级、肝纤维化诊断与分级、肝功能评估等。本文对DCE-MRI在肝脏中的应用和研究进展进行综述。 |
| 英文摘要: |
| Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a MR imaging method based on contrast agent pharmacokinetics, which can investigate microvascular structure and function. Liver accepts dual blood supply, and is affected by nearby organs' movement. As a result, there are more challenges of the application of DCE-MRI in the liver. But with the development of technique, more and more researches of DCE-MRI are applied in the liver, including antiangiogenesis targeted therapy drugs research, therapy monitor, prognosis evaluation, characterization and stage of masses, detection and grade of liver fibrosis and cirrhosis, evaluation of liver function, and so on. The application and research progresses of dynamic contrast-enhanced MRI in liver were reviewed in this article. |
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