| 张春艳,程敬亮,薛康康,张勇,陈苑,文宝红.鼻腔鼻窦神经内分泌癌的常规CT、MRI表现及ADC值[J].中国医学影像技术,2016,32(12):1857~1861 |
| 鼻腔鼻窦神经内分泌癌的常规CT、MRI表现及ADC值 |
| Conventional CT,MRI manifestations and ADC of sinonasal neuroendocrine carcinoma |
| 投稿时间：2016-06-02 修订日期：2016-08-24 |
| DOI：10.13929/j.1003-3289.2016.12.016 |
| 中文关键词: 鼻腔 鼻窦肿瘤 癌,神经内分泌 体层摄影术,X线计算机 磁共振成像 表观扩散系数 |
| 英文关键词:Nasal cavity Paranasal sinus neoplasms Carcinomas, neuroendocrine Tomography, X-ray computed Magnetic resonance imaging Apparent diffusion coefficient |
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| 中文摘要: |
| 目的 探讨鼻腔鼻窦神经内分泌癌（SNEC）的常规CT、MRI表现及ADC值特征。方法 回顾性分析经病理证实的25例SNEC的影像学资料，测量ADC值，并与鳞状细胞癌（25例）及腺样囊性癌（15例）的ADC值比较。结果 25例肿瘤中，直径>3.5 cm者19例（19/25，76.00%），呈不规则分叶状；直径<3.5 cm者6例（6/25，24.00%），呈椭圆形。病变累及全组副鼻窦及鼻腔6例，病变主体位于筛窦10例、蝶窦4例、上颌窦2例，局限于鼻腔3例。22例伴邻近组织广泛受累。20例接受CT检查示9例病灶密度均匀，11例呈不均匀密度软组织密度，其中5例可见斑点或线条样钙化影；16例可见骨质破坏。14例接受MRI示T1WI上呈等或稍低信号，T2WI上呈等或稍高信号为主的混杂信号。SNEC平均ADC值为（0.65±0.10）×10-3 mm2/s，明显低于鼻腔鼻窦鳞状细胞癌和腺样囊性癌。结论 SNEC的常规CT、MRI表现及ADC值具有一定的特征性，可为临床早期诊断提供依据。 |
| 英文摘要: |
| Objective To explore the conventional MRI, CT imaging features and apparent diffusion coefficient (ADC) appearance of sinonasal neuroendoerine carcinoma (SNEC). Methods Totally 25 cases of SNEC confirmed by pathology were analyzed retrospectively. The ADC values were measured and compared among SNEC, squamous cell carcinoma (n=25) and adenoid cystic carcinoma (n=15) in nasal and paranasal sinus. Results The diameters of SNEC in 19 cases (19/25, 76.00%) were >3.5 cm with irregular or lobulated shapes and 6 cases (6/25, 24.00%) were <3.5 cm, showing oval-shaped. Six cases located in the whole nasal and paranasal sinus system, and 10 cases of tumor centers located in ethmoid sinus, 4 in sphenoid sinus, 2 in maxillary sinus and 3 in nasal cavity. Twenty-two cases had invasion of adjacent structures. Among 20 patients undergoing CT examination, 9 cases showed even density and 11 cases showed uneven density with hypointense or hyperintense spots in 5 cases. Sixteen lesions demonstrated destruction of the adjacent bone structure. Among 14 patients undergoing MRI, lesions showed equal or low signal on T1WI and equal or sligthly high signal on T2WI. The mean ADC value of SNEC (×10-3 mm2/s) was lower than that of squamous cell carcinoma (×10-3 mm2/s, P<0.001) and adenoid cystic carcinoma (×10-3 mm2/s, P<0.001). Conclusion SNEC has certain characteristic features on conventional imaging and ADC value, which are helpful for the clinical diagnosis. |
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