| 肖莉玲,李颖嘉,马菲,洪少馥,张丽,张世玉,罗婉贤,罗淑仪.青年与中老年乳腺癌患者的临床病理及超声表现对比[J].中国医学影像技术,2016,32(9):1365~1369 |
| 青年与中老年乳腺癌患者的临床病理及超声表现对比 |
| Comparision of characteristics of clinicopathological and ultrasound between young and middle or elder breast carcinoma patients |
| 投稿时间：2016-02-07 修订日期：2016-04-11 |
| DOI：10.13929/j.1003-3289.2016.09.013 |
| 中文关键词: 乳腺肿瘤 病理学,临床 超声检查 青年女性 |
| 英文关键词:Breast neoplasms Pathology,clinical Ultrasonography Young women |
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| 中文摘要: |
| 目的 探讨青年与中老年乳腺癌患者的临床病理及超声表现。方法 对经手术病理证实的288例乳腺癌患者进行回顾性研究，分析青年组（≤35岁）和中老年组（>35岁）乳腺癌临床病理及超声图像特征的差异。结果 青年组较中老年组癌肿组织学分级高（P=0.03）、肿瘤偏大（P<0.01）、腋窝淋巴结易转移（P=0.03）、Ki-67表达增高（P=0.01）、三阴型多（P=0.04）、Luminal A型少（P=0.04）、肿块形状规则（P<0.05）、后方回声无衰减或回声增强（P=0.01）、边缘无毛刺征（P<0.01）及BI-RADS分类低（P=0.03）。 结论 与中老年比较，青年乳腺癌侵袭性强，预后差，但其超声表现偏向良性。 |
| 英文摘要: |
| Objective To explore the differences of clinicopathological and ultrasound images between the young (≤35 years old) and the middle or elder patients (>35 years old) with breast carcinoma. Methods Totally 288 patients with breast carcinoma confirmed by operation and pathology were studied retrospectively. The different features of clinicopathological and ultrasonic images between the young patients and the middle or elder patients with breast carcinoma were analyzed. Results Compared with the middle or elder patients, the young patients were more likely to be diagnosed with a higher grade (P=0.03), larger size (P<0.01), axillary lymph nodes positive (P=0.03), Ki-67 over-expression (P=0.01), triple negative (P=0.04), shape regular (P<0.05), posterior enhancement (P=0.01) and low BI-RADS category (P=0.03) and less likely to have been diagnosed with luminal A (P=0.04), no posterior shadowing (P=0.01), spiculated margin (P<0.01). Conclusion The breast carcinoma in young women is highly aggressive and poor prognosis, but it is partial benign in ultrasound. |
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