| 张超,陈楠,李坤成.内侧颞叶癫痫脑微结构变化磁共振研究进展[J].中国医学影像技术,2016,32(8):1290~1293 |
| 内侧颞叶癫痫脑微结构变化磁共振研究进展 |
| Research progresses of MRI on brain microstructure of medial temporal lobe epilepsy |
| 投稿时间：2016-01-04 修订日期：2016-04-19 |
| DOI：10.13929/j.1003-3289.2016.08.037 |
| 中文关键词: 癫痫 内侧颞叶 海马 磁共振成像 |
| 英文关键词:Epilepsy Medial temporal lobe Hippocampus Magnetic resonance imaging |
| 基金项目:国家“十二五”科技支撑计划课题项目（2012BAI10B04）、北京市医院管理局临床医学发展专项经费（ZYLX201609）。 |
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| 中文摘要: |
| 内侧颞叶癫痫（mTLE）是最常见的难治性癫痫，其发病机制不清，多与内侧颞叶及颞叶外脑区异常有关，如海马硬化和相关大脑皮层萎缩。随着磁共振及其后处理技术的进步，显示内侧颞叶及其与之相关区域的微结构变化，对mTLE的发病机制研究、术前准确定位及术后评估中有重要作用。本文对mTLE的脑微结构变化MRI的研究进展进行综述。 |
| 英文摘要: |
| Medial temporal lobe epilepsy (mTLE) is the most common type of intractable epilepsy, but the pathophysiologic mechanism still remains unclear currently. Previous studies suggest that it perhaps correlated with abnormal medial temporal structure and other extratemporal area, such as hippocampal sclerosis (HS) and related cortex atrophy. With the development of magnetic resonance and post-processing technologies, medial temporal structure and related brain area can be identified now, which can potentially make great contribution to the study of pathogenesis, preoperative lateralization and postoperative assessment of mTLE. The related progresses of MRI on brain microstructure of mTLE were reviewed in this paper. |
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