| 余芬,杨顺实,姜凤霞,李晶晶,张艺.超声斑点追踪成像技术评价多发性骨髓瘤患者的心肌功能[J].中国医学影像技术,2016,32(8):1214~1217 |
| 超声斑点追踪成像技术评价多发性骨髓瘤患者的心肌功能 |
| Speckle tracking imaging evaluation of left ventricular systolicfunction in multiple myeloma patients |
| 投稿时间：2015-11-17 修订日期：2016-03-23 |
| DOI：10.13929/j.1003.3289.2016.08.016 |
| 中文关键词: 多发性骨髓瘤 超声心动描记术 应变 |
| 英文关键词:Multiple myeloma Echocardiography Strain |
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| 中文摘要: |
| 目的 采用超声斑点追踪成像技术观察左心室射血分数（LVEF）正常的多发性骨髓瘤（MM）患者心肌收缩功能变化。方法 将40例多发性骨髓瘤患者（LVEF≥50%）分为室壁厚度正常组（n=13）及室壁厚度增厚组（n=27），以健康体检者40名为正常对照组，对所有受检者行常规超声参数测定及二维斑点追踪成像分析。结果 室壁厚度增厚组及室壁厚度正常组心尖部及左心室短轴位心肌各节段较正常对照组的二维纵向收缩期、二维径向收缩期峰值应变明显减低（P均<0.05），室壁增厚组减低更为明显。室壁厚度正常组、室壁厚度增厚组二尖瓣水平前壁、前间隔及室壁厚度增厚组乳头肌水平左心室后壁二维圆周收缩期峰值应变较正常对照组明显减低（P均<0.05），其余节段心肌二维圆周收缩期峰值应变差异无统计学意义（P均>0.05）。结论 MM患者在常规超声检查出现特征性改变之前，心肌纵向及径向收缩功能均已出现减低，但圆周运动未出现显著改变。 |
| 英文摘要: |
| Objective To evaluate regional myocardial systolic function by speckle tracking imaging in multiple myeloma (MM) with normal left ventricular ejection fraction (LVEF). Methods A total of 40 patients with MM and forty healthy controls (control group) were included, the general and 2D strain echocardiography parameters were analyzed. The MM patients were devided into normal ventricular wall group (n=13) and thickened ventricular wall group (n=27). Results The peak systolic longitudinal strain and peak systolic radial strain of different segments in patients with MM significantly reduced compared with those in control group (all P<0.05), and the thickened ventricular wall group was more lower (P<0.05). The peak systolic circumferential strain of anterior wall, anterior septal wall of mitral level in normal ventricular wall group and thickened ventricular wall group, left ventricular posterior wall of papillary muscle level in thickened ventricular wall group were all lower than those of control group (all P<0.05). The difference of the remaining two-dimensional myocardial segments circumferential peak systolic strain had no statistically significant (all P>0.05). Conclusion The peak systolic longitudinal strain and peak systolic radial strain in patient with MM has impaired before the characteristic echocardiogtaphy appearance, except the peak systolic circumferential strain. |
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