| 梁俊媚,丁康,徐艳燕,王璆,赵蕾.左心房容积追踪技术评价高尿酸血症患者左心房重构[J].中国医学影像技术,2016,32(1):57~62 |
| 左心房容积追踪技术评价高尿酸血症患者左心房重构 |
| Left atrial volume tracking technique evaluation of left atrial remodeling in hyperuricemia patients |
| 投稿时间：2015-05-18 修订日期：2015-10-27 |
| DOI：10.13929/j.1003-3289.2016.01.016 |
| 中文关键词: 高尿酸血症 心房功能,左 超声心动描记术 容积追踪 |
| 英文关键词:Hyperuricemia Atrial function,left Echocardiography Volume tracking |
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| 中文摘要: |
| 目的 探讨左心房容积追踪(LAVT)技术评价高尿酸血症(HUA)患者左心房容积和功能变化的价值。方法 选取HUA患者59例,分为无症状HUA组(37例)和痛风组(22例),选取血尿酸正常者36例(对照组)。采用LAVT技术得到3组左心房容积指数 及功能指数,比较3组以上参数的差异。结果 3组LAVImax、LAVIpre、LAVI比较,差异均有统计学意义(F=9.92、12.45、19.54,P均<0.05);无症状HUA组和痛风组LAVImax大于对照组(q=5.30、5.40,P均<0.05),无症状HUA组和痛风组LAVIpre大于对照组(q=5.50、6.38,P均<0.05),无症状HUA组LAVImin大于对照组(q=6.34,P<0.05),痛风组LAVImin大于无症状HUA组(q=2.84,P<0.05)。3组dv/dtS、dv/dtA、LAtEF、LApEF和LAaEF比较,差异均有统计学意义(F=4.16、4.24、19.41、6.74、18.88,P均<0.05);无症状HUA组、痛风组dv/dtS值大于对照组(q=2.84、3.88,P均<0.05),痛风组dv/dtA值大于对照组、无症状HUA组(q=4.12、2.64,P均<0.05),对照组LAtEF大于无症状HUA组、痛风组(q=5.56、8.90,P均<0.05),无症状HUA组LAtEF大于痛风组(q=4.14,P<0.05),对照组LAaEF大于无症状HUA组、痛风组(q=5.08、8.82,P均<0.05),无症状HUA组LAaEF大于痛风组(q=4.41,P<0.05)。结论 LAVT技术可实时追踪高尿酸血症左心房重构,随血尿酸水平增高及临床症状加重,左心房重构越来越明显。 |
| 英文摘要: |
| Objective To explore the value of left atrial volume tracking (LAVT) to assess the changes of left atrial (LA) volume and function in hyperuricemia patients. Methods Totally 59 hyperuricemia subjects were divided into asymptomatic hyperuricemia group (n=37) and gouty group (n=22), and 36 cases with normal serum uric acid were enrolled as control group. Left atrial volume index including LA maximal volume index (LAVImax), LA presystolic volume index (LAVIpre), LA minimal volume index (LAVImin) and function index including systolic LA filling rate (dv/dtS), early diastolic LA emptying rate (dv/dtE), late diastolic LA emptying rate (dv/dtA) were measured by LAVT. The parameters among three groups were compared. Results LAVImax, LAVIpre and LAVImin were statistical significant among the three groups (F=9.92, 12.45,19.54, all P<0.05); LAVImax in asymptomatic hyperuricemia group and gouty group were higher than that in control group (q=5.30, 5.40, all P<0.05), LAVIpre in asymptomatic hyperuricemia group and gouty group were higher than that in control group (q=5.50, 6.38, all P<0.05), LAVImin in asymptomatic hyperuricemia group was higher than that in control group (q=6.34, P<0.05), LAVImin in gouty group was higher than that in asymptomatic hyperuricemia group (q=2.84, P<0.05). dv/dtS, dv/dtA, LAtEF, LApEF and LAaEF were statistical significant among the three groups (F=4.16, 4.24, 19.41, 6.74, 18.88, all P<0.05); dv/dtS in asymptomatic hyperuricemia group and gouty group were higher than that in control group (q=2.84, 3.88, all P<0.05), dv/dtA in gouty group was higher than that in control group and asymptomatic hyperuricemia group (q=4.12, 2.64, all P<0.05), LAtEF in control group was higher than that in asymptomatic hyperuricemia group and gouty group (q=5.56, 8.90, all P<0.05), LAtEF in asymptomatic hyperuricemia group was higher than that in gouty group (q=4.14, P<0.05), LAaEF in control group was higher than that in asymptomatic hyperuricemia group and gouty group (q=5.08, 8.82, all P<0.05), LAaEF in asymptomatic hyperuricemia group was higher than that in gouty group (q=4.41, P<0.05). Conclusion LAVT can be used to track left atrial remodeling of hyperuricemia patients in real time. With the increasing of uric acid level and the deterioration of the clinical symptoms, left atrial remodeling is becoming more and more obvious. |
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