| 石晓辰,唐少珊,于宏伟.超声造影诊断良恶性甲状腺结节Meta分析[J].中国医学影像技术,2015,31(3):355~358 |
| 超声造影诊断良恶性甲状腺结节Meta分析 |
| Contrast-enhanced ultrasonography in diagnosis of benign and malignant thyroid nodules: A Meta-analysis |
| 投稿时间：2014-08-21 修订日期：2015-01-02 |
| DOI：10.13929/j.1003-3289.2015.03.009 |
| 中文关键词: 甲状腺结节 超声检查 Meta分析 |
| 英文关键词:Thyroid nodules Ultrasonography Meta-analysis |
| 基金项目:辽宁省自然科学基金(2014021051)。 |
|
| 摘要点击次数: 2359 |
| 全文下载次数: 1479 |
| 中文摘要: |
| 目的 对研究超声造影诊断甲状腺结节良恶性的文献进行Meta分析,评价超声造影对甲状腺结节良恶性的诊断价值。方法 检索中国期刊网、OVID、PubMed,运用Meta.disc1.4软件对纳入文献的原始数据进行汇总计算,计算合并敏感度(SE)、特异度(SP)、诊断比值比(DOR)等相关数值,绘制合并受试者工作特征(SROC)曲线,计算曲线下面积(AUC),评价超声造影对甲状腺结节良恶性的诊断价值。结果 共有11篇文献符合纳入标准,文献之间存在较高异质性,按照随机效应模型计算得到合并SE、SP、DOR及相应的95%可信区间分别为86.9%(95%可信区间:83.0%~89.9%)、91.4%(95%可信区间:89.2%~93.3%)、69.288(95%可信区间:38.79~123.77)、AUC为0.9550,Q指数为0.8973。结论 超声造影对诊断甲状腺结节良恶性有较高的临床应用价值。 |
| 英文摘要: |
| Objective To comprehensive analysis on literature about CEUS in diagnosis of benign and malignant thyroid nodules, and to evaluate the diagnosis value of CEUS for benign and malignant thyroid nodules. Methods CNKI, OVID, PubMed were searched. The original data of included literature were analyzed, the pooled sensitivity, specificity, diagnostic odds ratios with Meta.disc1.4 version were calculated, summary ROC curve was depicted, the area under the curve (AUC) was obtained, then the diagnosis value of CEUS for benign and malignant thyroid nodules were evaluated. Results A total of 11 articles met the inclusion criteria, there was a high heterogeneity between literature, and the random effects model combined sensitivity, specificity, diagnostic odds ratios and corresponding 95% confidence intervals was 86.9% (95%CI 83.0%—89.9%), 91.4% (95%CI 89.2%—93.3%),69.288 (95%CI 38.79—123.77), respectively. The AUC was 0.9550, Q index was 0.8973. Conclusion CEUS has a high value in distinguishing benign and malignant thyroid nodules. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
