邓燕云,王全师,吴湖炳.比较胃肠间质瘤与胃肠原发淋巴瘤18F-FDG PET/CT征象[J].中国医学影像技术,2014,30(6):881~884
比较胃肠间质瘤与胃肠原发淋巴瘤18F-FDG PET/CT征象
18F-FDG PET/CT features of gastrointestinal stromal tumor and primary gastrointestinal lymphoma:Comparison analysis
投稿时间:2014-04-02  修订日期:2014-04-30
DOI:
中文关键词:  胃肠道间质肿瘤  淋巴瘤  氟脱氧葡萄糖F18  体层摄影术,发射型计算机,单光子
英文关键词:Gastrointestinal stromal tumors  Lymphoma  Fluorodeoxyglucose F18  Tomography,emission-computed,single-photon
基金项目:
作者单位E-mail
邓燕云 南方医科大学南方医院PET中心, 广东 广州 510515  
王全师 南方医科大学南方医院PET中心, 广东 广州 510515 wqslph@tom.com 
吴湖炳 南方医科大学南方医院PET中心, 广东 广州 510515  
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中文摘要:
      目的 比较胃肠间质瘤(GIST)与胃肠原发淋巴瘤(PGIL)18F-FDG PET/CT征象的差异。方法 回顾性分析经病理证实的21例GIST患者和26例PGIL患者的18F-FDG PET/CT资料,计算CT和18F-FDG PET对病变的检出率,比较GIST和PGIL病灶最大标准摄取值(SUVmax)和最大厚度(THKmax)及18F-FDG PET/CT征象差异。结果 CT检出20例(20/21,95.24%)GIST、24例(24/26,92.31%)PGIL;18F-FDG PET对GIST和PGIL检出率均为100%。PGIL病灶SUVmax显著高于GIST(11.14±7.78 vs 7.30±4.44,P<0.05),二者THKmax差异无统计学意义[(5.61±4.30)cm vs(3.80±2.16)cm,P>0.05]。GIST多为单发病灶(14/21,66.67%),以胃肠壁局限性增厚为主(18/21,85.71%),1例(1/21,4.76%)继发性肠腔扩张,7例发生转移;PGIL多为多发病灶(15/26,57.69%),以胃肠壁弥漫性增厚为主(15/26,57.69%),5例(5/26,19.23%)继发性肠腔扩张,20例发生转移。结论 GIST和PGIL的18F-FDG PET/CT特点各异,有助于鉴别诊断。
英文摘要:
      Objective To compare the 18F-FDG PET/CT features of gastrointestinal stromal tumor (GIST) and primary gastrointestinal lymphoma (PGIL). Methods 18F-FDG PET/CT data of 21 patients with GIST and 26 patients with PGIL confirmed by pathology were retrospectively analyzed. The detection rate of CT and 18F-FDG PET in detecting GIST and PGIL were calculated. The maximal standard uptake value (SUVmax) and maximal thickness (THKmax) of the lesions and the signs of 18F-FDG PET/CT in GIST and PGIL were compared. Results Twenty GIST were detected by CT with detection rate of 95.24% (20/21), and 24 PGIL were detected with detection rate of 92.31% (24/26). The detection rate of 18F-FDG PET was 100% in both GIST and PGIL. SUVmax of PGIL was significantly higher than that of GIST (11.14±7.78 vs 7.30±4.44, P<0.05).No significant difference was found in THKmax of GIST and PGIL [(5.61±4.30)cm vs (3.80±2.16)cm, P>0.05). Most of GIST were single (14/21, 66.67%) with local thickened gastrointestinal wall (18/21, 85.71%), secondary enteric cavity dilatation was observed in 1 case (1/21, 4.76%), while metastases occurred in 7 cases. Most of PGIL cases were multiple (15/26, 57.69%) with diffuse thickened gastrointestinal wall (15/26, 57.69%), secondary enteric cavity dilatation was observed in 5 cases (5/26, 19.23%), while metastases occurred in 20 cases. Conclusion 18F-FDG PET/CT features of GIST and PGIL are distinctly different, being helpful to differential diagnosis.
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