| 韦超,董江宁,李乃玉,韦树华,高飞.3.0T MR肝脏三维容积内插快速采集多期增强联合DWI在宫颈癌治疗前评估和分期中的价值[J].中国医学影像技术,2013,29(12):2015~2019 |
| 3.0T MR肝脏三维容积内插快速采集多期增强联合DWI在宫颈癌治疗前评估和分期中的价值 |
| Value of 3.0T MR LAVA-Flex multi-phase enhancement techniques combined with DWI in preoperative evaluation and staging of cervical cancer |
| 投稿时间：2013-06-08 修订日期：2013-10-29 |
| DOI： |
| 中文关键词: 肝脏三维容积内插快速采集 扩散磁共振成像 宫颈肿瘤 分期 治疗 |
| 英文关键词:Liver acceleration volume acquisition Diffusion magnetic resonance imaging Uterine cervical neoplasms Staging Therapy |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨3.0T MR肝脏三维容积内插快速采集（LAVA-Flex）增强技术联合DWI在宫颈癌治疗前评估和分期中的价值。方法 收集病理诊断为宫颈癌且治疗前接受MR检查的46例患者，其中29例接受手术治疗。综合应用LAVA-Flex增强技术、DWI、常规SE序列对宫颈癌进行影像学分期，评估宫颈肿块浸润范围和盆腔淋巴结转移，与临床分期或手术病理进行对照研究。结果 ①与术后病理比较，29例宫颈癌MR分期准确率（27/29，93.10%）明显高于传统临床分期（18/29，62.07%，P<0.05）。②LAVA-Flex增强扫描评估肿瘤侵犯的准确率为97.73%（86/88），T2WI联合DWI的准确率为96.59%（85/88），两者联合应用准确率为98.86%（87/88）。③LAVA-Flex增强扫描结合DWI诊断淋巴结转移的准确率为89.47%（17/19），敏感度100%（10/10），特异度81.82%（9/11）。结论 LAVA-Flex增强技术联合DWI能准确、迅速地对宫颈癌进行分期，并能对宫颈癌治疗相关指标进行综合评估。 |
| 英文摘要: |
| Objective To explore the value of LAVA-Flex and DWI sequence in preoperative assessment and staging of cervical cancer. Methods Totally 46 patients with cervical cancer proved by pathology and underwent MR before treatment were collected, among them 29 patients underwent surgical operation. Radiological staging was performed with LAVA-Flex, DWI and spin echo sequences to describe tumor infiltration and lymph node metastasis, and the results were compared with those of clinical staging or pathology. Results ①Compared with postoperative pathology, the accuracy of MR staging (27/29, 93.10%) was significantly higher than that of traditional clinical stage (18/29, 62.07%) in 29 cases of cervical cancer (P<0.05). ②The accuracy of contrast material-enhanced LAVA-Flex imaging in detecting neoplasm invasiveness was 97.73% (86/88), of T2WI with DWI was 96.59% (85/88), while of combination of these two methods was 98.86% (87/88). ③The accuracy, sensitivity and specificity of contrast material-enhanced LAVA-Flex imaging with DWI in detecting lymph node metastasis was 89.47% (17/19), 100% (10/10) and 81.82% (9/11), respectively. Conclusion Contrast-enhanced LAVA-Flex combined with DWI is accurate and rapid in staging of cervical cancer, which can be used to evaluate treatment-related indicators of cervical cancer. |
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