| 赵一冰,李佩玲,王永峰,赵卫华.屏气磁共振电影成像评价不同年龄组健康国人心脏结构和功能[J].中国医学影像技术,2012,28(6):1122~1126 |
| 屏气磁共振电影成像评价不同年龄组健康国人心脏结构和功能 |
| Assessment of cardiac structure and function with breath-hold cine MRI in healthy Chinese volunteers in different ages |
| 投稿时间：2011-11-21 修订日期：2012-02-10 |
| DOI： |
| 中文关键词: 磁共振成像 屏气电影 心功能 |
| 英文关键词:Magnetic resonance imaging Breath-hold cine Cardiac function |
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| 中文摘要: |
| 目的 应用屏气磁共振电影成像建立20~70岁之间健康国人心脏结构和fMRI定量分析数据库,探讨年龄及性别因素对心脏结构和功能的影响。方法 采用快速稳态平衡进动序列(FIESTA)对100名健康成人进行MR电影成像,用心功能软件Report Card计算心脏结构和功能参数。结果 左心房内径、主动脉根部横径、前室间隔厚度、左心室后壁厚度随年龄增长而呈不同程度增加,而舒张末期左心室内径、收缩末期左心室内径均无明显改变,性别间有统计学差异,女性测值较男性略小。射血分数、心输出量、心脏指数随年龄增长均无明显改变,性别间差异无统计学意义;峰值填充率随年龄增长逐渐减小,性别间差异无统计学意义。左心室心肌质量随年龄的增长逐渐增加后又逐渐减少,性别间有统计学差异,女性测值较男性小。结论 本研究建立的20~70岁健康国人心脏结构和fMRI正常值范围可为判断心脏结构和功能的异常提供量化依据。 |
| 英文摘要: |
| Objective To establish a quantitative database of cardiac structure and left ventricular function parameters with breath-hold cine MRI for normal Chinese aged between 20 to 70 years old, and to analyze the impact of gender and age on correlation of these parameters. Methods A total of 100 healthy volunteers underwent fast imaging employing steady-state acquisition (FIESTA) cine MR examination. All MR images were processed on Report Card software to test the cardiac structure and function. Results As age increasing, the left atrial diameter, aortic root diameter, anterior septal wall thickness, posterior left-ventricular wall thickness increased to different degrees, the end diastolic diameter and end systolic diameter had no significant changes. The measured data of male group were slightly higher than those of female group. The ejection fraction, cardiac output, cardiac index had no significant change along with the increase of age, and no statistical difference was found between the sexes. The peak filling rate gradually reduced with age increasing, and had no statistical difference between the sexes. The left ventricular myocardial mass increased first then reduced gradually, and the measured data of male group were higher than those of female group. Conclusion The normal range of cardiac structure and left ventricular function parameters for healthy Chinese aged between 20 to 70 are obtained, providing a quantitative basis for left ventricular dysfunction determination. |
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