刘利,王志刚,任建丽,容跃,欧艳.实时三维超声心动图评价冠心病患者左前降支冠状动脉PCI术后左心室整体及局部收缩功能与同步性[J].中国医学影像技术,2012,28(4):680~684
实时三维超声心动图评价冠心病患者左前降支冠状动脉PCI术后左心室整体及局部收缩功能与同步性
Real-time three-dimensional echocardiographic evaluation on the whole and regional left ventricular systolic function and synchrony in coronary artery disease patients after PCI of left anterior descending branch
投稿时间:2011-08-09  修订日期:2011-12-14
DOI:
中文关键词:  超声心动描记术,三维  冠状动脉疾病  心室功能,左  同步性
英文关键词:Echocardiography, three-dimensional  Coronary disease  Ventricular function, left  Synchrony
基金项目:国家自然科学基金项目面上项目(81071158)、国家青年科学基金(81000621)。
作者单位E-mail
刘利 重庆医科大学超声影像学研究所 重庆医科大学附属第二医院超声科, 重庆 400010  
王志刚 重庆医科大学超声影像学研究所 重庆医科大学附属第二医院超声科, 重庆 400010  
任建丽 重庆医科大学超声影像学研究所 重庆医科大学附属第二医院超声科, 重庆 400010 renjianli_1977@163.com 
容跃 重庆医科大学超声影像学研究所 重庆医科大学附属第二医院超声科, 重庆 400010  
欧艳 重庆医科大学超声影像学研究所 重庆医科大学附属第二医院超声科, 重庆 400010  
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中文摘要:
      目的 探讨实时三维超声心动图(RT-3DE)评价冠心病左前降支冠状动脉经皮介入治疗(PCI)后患者左心室整体及局部收缩功能与同步性的应用价值。 方法 对30例接受左前降支PCI术的患者分别于术前、术后1周,1、3个月应用RT-3DE进行17节段时间-容积曲线分析,获得左心室舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)及左心室16节段达到最小收缩容积时间差的标准差校正值(Tmsv-16-SD%),即收缩不同步指数(SDI);同时得到前壁、前间隔及心尖帽共7节段的舒张末期容积(rEDV)、收缩末期容积(rESV)、节段射血分数(rEF)及节段达到最小收缩容积时间的校正值(Tmsv%)。 结果 术后1个月EDV、ESV、rESV及大部分节段的rEDV低于术前及术后1周(P<0.05),EF、rEF高于术前及术后1周(P<0.05),Tmsv-16-SD%及局部节段Tmsv%低于术前(P<0.05),与术后1周无明显差异(P>0.05);术后3个月ESV、Tmsv-16-SD%及大部分节段的rEDV、rESV、Tmsv%低于术前、术后1周及术后1个月(P<0.05),EF及大部分节段的rEF高于术前、术后1周及术后1个月(P<0.05),rEDV低于术前及术后1周,与术后1个月相比较无明显差异(P>0.05)。 结论 利用RT-3DE能定量评价冠心病患者左前降支PCI术后左心室整体及局部收缩功能与同步性的改善情况。
英文摘要:
      Objective To assess the clinical value of real-time three-dimensional echocardiography (RT-3DE) in evaluating the whole and regional left ventricular systolic function and synchrony in coronary artery disease patients after percutaneous transluminal coronary intervention (PCI) of left anterior descending (LAD). Methods RT-3DE was performed on 30 patients before PCI of LAD and 1 week, 1 and 3 months after PCI. The 17-segmental time-volumetric curves were analyzed, and the global systolic function parameters (EDV, ESV, EF) and synchronic parameters (Tmsv 16-SD%) were obtained. Tmsv 16-SD% was served as the systolic dyssynchrony index (SDI). Regional systolic function parameters (rEDV, rESV, rEF) and synchronic parameters (Tmsv%) were also obtained. Results Compared with before and 1 week after PCI, the global EDV, ESV, rESV and rEDV of most segments decreased 1 month later (P<0.05), while the EF and rEF increased (P<0.05). Tmsv-16-SD% and Tmsv% of some segments decreased compared with those preoperation (P<0.05), while no statistical difference was found with 1 week after PCI (P>0.05). Three months after PCI, the global ESV, Tmsv-16-SD% and rEDV, rESV, Tmsv% of most segments group decreased (P<0.05), while the EF and rEF of most segments increased (P<0.05), the global rEDV decreased compared with preoperation and 1 week after PCI (P<0.05), while no statistical difference was found with 1 month after PCI (P>0.05). Conclusion RT-3DE is a useful method in assessing the whole and regional left ventricular systolic function and synchrony in coronary artery disease patients after PCI of LAD.
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