| 王瑞,张臣,于薇,雒芳芳,张兆琪.64层螺旋CT冠状动脉成像评价可疑冠心病患者预后[J].中国医学影像技术,2011,27(9):1804~1807 |
| 64层螺旋CT冠状动脉成像评价可疑冠心病患者预后 |
| Prognostic value of 64-slice CT coronary angiography in patients with suspected coronary artery disease |
| 投稿时间：2011-03-14 修订日期：2011-06-15 |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 冠状血管造影术 预后 冠状动脉疾病 |
| 英文关键词:Tomography, X-ray computed Coronary angiography Prognosis Coronary disease |
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| 中文摘要: |
| 目的 探讨64层螺旋CT冠状动脉成像(64-CTCA)判断可疑冠心病患者预后的价值。 方法 收集1092例接受64-CTCA检查的患者,分析其CTA结果,评估影响患者预后的危险因素。随访终点事件包括心源性死亡、心肌梗死、不稳定型心绞痛以及住院接受经皮冠状动脉介入治疗(PCI)、冠状动脉搭桥术(CABG)、溶栓治疗。 结果 39例患者失访,14例患者因图像质量较差、不能用于评价而被排除。平均随访(22.74±7.27)个月。764例检查正常者中,1例死亡,4例发生心脏事件;174例冠状动脉狭窄<50%患者中,7例发生心脏事件;101例冠状动脉狭窄≥50%患者中,4例死亡,62例发生心脏事件;三者年事件发生率分别为0.65%,4.02%和65.35%。冠状动脉狭窄程度、狭窄位置及斑块类型均为影响预后的危险因素(HR=14.586,95%CI=8.751~24.313;HR=2.624, 95%CI=2.275~3.027;HR=1.648,95%CI= 1.204~2.257;P均<0.001)。 结论 64-CTCA能够为可疑冠心病患者提供预后参考信息,64-CTCA检查正常者预后较好。 |
| 英文摘要: |
| Objective To assess the prognostic value of 64-slice CT coronary angiography (64-CTCA) in patients with suspected coronary artery disease (CAD). Methods Totally 1092 consecutive patients with suspected CAD underwent 64-CTCA. The results were analyzed and risk factors impacting prognosis were evaluated. Patients were followed up for the occurrence of cardiac death, nonfatal myocardial infarction, unstable angina and requiring hospitalization. Results A total of 39 patients were lost during follow-up, and 14 were excluded as a result of low quality images. During the follow-up of (22.74±7.27) months, 1 patient died and 4 had cardiac events in 764 patient with normal 64-CTCA results, 7 had severe cardiac events in 174 patients of coronary stenosis <50%, and 62 had severe cardiac events in 101 patients of coronary stenosis ≥50%. The rate of cardiac events was 0.65%, 4.02% and 65.35%, respectively. The extent of stenosis, locations and components of plaques were recognized as risk factors of cardiac events (HR=14.586, 95%CI=8.751—24.313; HR=2.624, 95%CI=2.275—3.027; HR=1.648, 95%CI=1.204—2.257; all P<0.001). Conclusion To patients with suspected CAD, 64-CTCA has significant prognostic impact on the prediction of cardiac events. Normal CAD results identify good prognosis. |
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