| 丁献敏,刘保平,韩星敏,程兵,阮翘.全身骨显像在婴幼儿朗格汉斯组织细胞增多症诊断和分期中的应用[J].中国医学影像技术,2011,27(6):1276~1278 |
| 全身骨显像在婴幼儿朗格汉斯组织细胞增多症诊断和分期中的应用 |
| Application of whole-body bone scintigraphy in diagnosis and staging of Langerhans cell histiocytosis in infants |
| 投稿时间：2010-12-14 修订日期：2011-02-21 |
| DOI： |
| 中文关键词: 组织细胞增多症,朗格汉斯细胞 放射性核素显像 全身显像 婴儿 |
| 英文关键词:Histiocytosis, Langerhans-cell Radionuclide imaging Whole body imaging Infant |
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| 中文摘要: |
| 目的 探讨全身骨显像在婴幼儿朗格汉斯组织细胞增多症(LCH)诊断和分期中的应用价值。方法 对20例经手术病理或骨髓穿刺、皮疹压片细胞学确诊为LCH的婴幼儿行全身骨显像检查,对骨显像阳性者加行局部X线或CT检查。利用ROI技术计算全身骨显像阳性病灶的F/N比值并求出位于相同部位病灶的F/N比值均值。结果 20例患儿全身骨显像10例阳性,4例为多发病灶,6例为单发病灶。单纯颅骨放射分布异常3例,颅骨合并其他部位骨3例,肩胛骨2例,肋骨1例,下肢骨1例;单发颅骨病灶的F/N比值均值为0.36,长骨病灶的F/N比值均值为3.52。结论 全身骨显像有助于婴幼儿LCH的诊断及分期。 |
| 英文摘要: |
| Objective To assess the application value of whole-body bone scintigraphy in diagnosis and staging of Langerhans cell histiocytosis (LCH) in infants. Methods Whole-body bone scintigraphy was performed in 20 infants of LCH confirmed with surgical pathology or bone marrow aspiration and laboratory data. The infants with positive bone scintigraphy underwent X-ray or CT, and the F/N value of positive lesions and lesions located in the same area were calculated by ROI technology. Results Ten of 20 patients showed positive in bone scans, including 4 with multi-focal lesions and 6 with single lesion. Among 10 patients with positive scintigrams, there were 3 patients with abnormal bone uptakes limited to cranial, 3 with cranial and other parts of abnormal bone uptakes, 2 with scapula abnormal uptakes, as well as rib and lower limb bone involvement (each n=1). The average ratios of F/N on cranial alone was 0.36, while focused on long bones was 3.52. Conclusion Whole-body bone scintigraphy is useful in the diagnosis and staging of LCH in infants. |
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