| 周文兰,钟锦梅,吴湖炳,王全师.同时性多发原发癌治疗前的18F-FDG PET/CT显像[J].中国医学影像技术,2011,27(4):804~808 |
| 同时性多发原发癌治疗前的18F-FDG PET/CT显像 |
| Detection of pre-therapy synchronous multiple primary carcinomas with 18F-FDG PET/CT |
| 投稿时间：2010-09-26 修订日期：2010-11-12 |
| DOI： |
| 中文关键词: 肿瘤 正电子发射型体层摄影术 18F氟脱氧葡萄糖 体层摄影术,X线计算机 |
| 英文关键词:Neoplasms Positron-emission tomography Fluorodeoxyglucose F18 Tomography, X-ray computed |
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| 中文摘要: |
| 目的 探讨对同时性多发原发癌患者治疗前进行18F-FDG PET/CT显像的价值。方法 回顾性分析经手术或活组织病理学检查确诊的治疗前同时性多发原发癌患者11例,均接受全身18F-FDG PET/CT检查,通过诊断试验法计算PET/CT检查的灵敏度。结果 治疗前11例同时性多发原发癌患者中,7例(7/11,63.64%)肿瘤来源于消化系统;共检出病灶25个,包括食管7个、胃部4个、结肠5个、直肠2个,肺部4个,喉部2个,骨髓1个,其中18个(18/25,72.00%)肿瘤起源于消化系统。PET/CT诊断灵敏度为88.00%。假阴性发生在肺泡细胞癌、黏液腺癌及微小病灶;假阳性发生在腺瘤性息肉。2例无症状查体者PET/CT检查发现多发原发癌,其中1例接受5次PET/CT检查,PET/CT随访无肿瘤复发。3例患者在明确原发灶、寻找转移灶过程中发现第二原发癌。结论 PET/CT在同时性多发原发癌的发现及诊断中具有一定价值。 |
| 英文摘要: |
| Objective To observe the value of 18F-FDG PET/CT on the detection of pre-therapy synchronous multiple primary carcinomas (MPC). Methods Eleven patients with pre-therapy synchronous MPC confirmed with surgery or biopsy were analyzed. All the patients received whole body PET/CT examination, and the sensitivity of PET/CT was calculated with diagnosis test. Results Of 11 patients with pre-therapy synchronous MPC, tumors came from gastrointestinal tract in 7 patients (7/11, 63.64%). Twenty-five primary lesions were found in the following locations, including 7 in esophagus, 4 in stomach, 5 in colon, 2 in rectum, 4 in lung, 2 in throat and 1 in bone marrow. Totally 18 lesions (18/25, 72.00%) were in gastrointestinal tracts. The sensitivity of PET/CT detecting primary tumor was 88.00%. False-negative PET/CT findings were mainly related to bronchoalveolar carcinoma, mucinous adenocarcinoma and small lesions, while false-positive PET/CT findings were mainly related to the intestine due to benign polyps. Two patients of synchronous MPC were discovered in symptomless people that undergoing routine physical examination, one of which received 5 times of PET/CT examination, and the tumors completely released during following-up. In 3 patients, the second cancer were found after the first cancer had been diagnosed. Conclusion 18F-FDG PET/CT is useful in finding and diagnosing pre-therapy synchronous MPC. |
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