SHEN Bao-zhong,WANG Dan,WANG Kai,SUN Fei.The clinical application of whole body diffusion weightedimaging (WB-DWI) for detecting tumor[J].中国医学影像技术,2010,26(s1):224
The clinical application of whole body diffusion weightedimaging (WB-DWI) for detecting tumor
  
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SHEN Bao-zhong Department of Radiology,the Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,China 
WANG Dan Department of Radiology,the Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,China 
WANG Kai Department of Radiology,the Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,China 
SUN Fei MR Modality,GE Healthcare[China],Beijing100176,China 
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中文摘要:
      Objective To evaluate the clinical application of whole body diffusion weighted imaging (WB-DWI) for tumor detection, and compare with PET/CT. Methods Twelve patients with malignancies (3 pulmonary carcinoma patients; 3 liver cancer patients, 2 breast cancer patients and 1 pancreatic carcinoma patient, 1 thyroid cancer patient, 1 liposarcoma patient, 1 nasopharyngeal carcinoma patient) underwent WB-DWI and PET/CT in seven days to detect tumor. All patients were followed by histology or clinical-radiological examination in seven days. WB-DWI was performed using the built-in quadrature body coil and a five-station short TI inversion recovery-echo planar imaging (STIR-EPI) sequence with TR=4500 ms, TE=106 ms, TI=160 ms, b=0, 600 s/mm2, slice thickness/gap: 7 mm/-1 mm. The prescan procedure of STIR-EPI was modified and center frequency (CF) was optimized during each exam. The ADC values were computed on the ADC map and compared between benign and malignant lesions. Results Totally, Forty-six lesions were detected in 10 of 12 patients with WB-DWI, and 41 lesions in 9 patients with PET. The ADC values between benign and malignant lesions had no significant difference. Conclusion WB-DWI has a clinical potential application for detecting tumor. ADC values appear few value in differentiating benign lesions from malignant diseases.
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