| 邵丹,王淑侠,梁长虹.18F-FDG PET/CT鉴别诊断心包良、恶性病变[J].中国医学影像技术,2010,26(2):333~336 |
| 18F-FDG PET/CT鉴别诊断心包良、恶性病变 |
| Differentiation of malignancy from benign in pericardial lesions with 18F-FDG PET/CT |
| 投稿时间：2009-06-18 修订日期：2009-11-06 |
| DOI： |
| 中文关键词: 心包 心脏肿瘤 体层摄影术,X线计算机 正电子发射型体层摄影术 诊断,鉴别 |
| 英文关键词:Pericardium Heart neoplasms Tomography, X-ray computed Positron-emission tomography Diagnosis, differential |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT鉴别诊断心包良、恶性病变的可行性及诊断价值。方法 收集16例心包病变患者的18F-FDG PET/CT资料,其中恶性9例,良性7例。测得病灶SUVmax值,并观察病灶内部密度及与周围组织关系。对病变或心包穿刺液行病理学检查,确定良恶性。结果 恶性病变及良性病变SUVmax分别为10.1±6.0、3.0±2.1(P<0.01)。以病灶SUVmax值3.5~4.5作为鉴别心包病变良恶性的阈值,判断心包病变的灵敏度为100%、特异度为85.71%、准确率为93.75%、阳性预测值为90.00%、阴性预测值为100%。结论 18F-FDG PET/CT可较准确地鉴别诊断心包病变的良、恶性。 |
| 英文摘要: |
| Objective To assess the feasibility of 18F-FDG PET/CT for differentiation of malignancy from benign in pericardial Lesions. Methods 18F-FDG PET/CT data of 16 patients with pericardial lesions (9 malignancy, 7 benign) were analyzed using maximum standard uptake values (SUVmax) and the density of lesions, the relationship with surrounding tissues were also evaluated. The results of malignancy or benign were proved by needle biopsy.Results SUVmax of malignancy (10.1±6.0) and benign (3.0±2.1) was significant different (P<0.01). Taking the optimal cut-off value as SUVmax 3.5—4.5, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of differentiation of malignant from benign in pericardial lesions was 100%, 85.71%, 93.75%, 90.00% and 100%, respectively. Conclusion 18F-FDG PET/CT can predict benign or malignance of pericardial lesions with moderate accuracy. |
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