| 梁颖,吴宁,李蒙,郑容,刘瑛,张雯杰,李静,赵平.18F-FDG PET/CT在查找骨转移瘤原发灶中的价值[J].中国医学影像技术,2009,25(12):2275~2278 |
| 18F-FDG PET/CT在查找骨转移瘤原发灶中的价值 |
| Value of 18F-FDG PET/CT in detecting primary tumor in patients with bone metastases |
| 投稿时间：2009-02-11 修订日期：2009-08-19 |
| DOI： |
| 中文关键词: 骨肿瘤 体层摄影术,发射型计算机 体层摄影术,X线计算机 18F氟脱氧葡萄糖 |
| 英文关键词:Bone neoplasms Tomography, emission computed Tomography, X-ray computed Fluorodeoxyglucose F18 |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT在查找骨转移瘤原发灶中的应用价值及不同类型骨转移瘤的PET/CT特点。方法 回顾性分析34例原发灶不明的骨转移瘤患者病例资料,经常规检查未发现原发灶,行18F-FDG PET/CT扫描查找原发灶。比较溶骨性转移瘤和成骨性转移瘤SUVmax的差异。结果 经组织细胞学或3个月以上的临床随访证实,34例患者中,PET/CT检出22例原发灶(64.71%)。12例PET/CT未发现原发灶(35.29%)。23例溶骨性为主转移瘤和11例成骨性为主转移瘤的SUVmax分别为6.78±3.66和4.13±1.69(P<0.05)。结论 18F-FDG PET/CT显像可提示多数骨转移瘤患者的原发灶,进而指导患者的治疗计划。溶骨性转移瘤的代谢活性较成骨性转移瘤更高。 |
| 英文摘要: |
| Objective To assess the value of 18F-FDG PET/CT in detecting primary tumors of patients with bone metastases, and to observe PET/CT characteristics of different types of bone metastases. Methods Whole-body 18F-FDG PET/CT images of 34 patients with metastatic bone from unknown primary tumor (CUP) were retrospectively analyzed, and SUVmax was compared in osteolytic and osteoblastic subgroups based on CT characteristics. Results Diagnosis of these patients were confirmed by histopathological findings or ≥3 months follow-up. Primary tumors were detected with PET/CT in 22 patients (64.71%). SUVmax was 6.78±3.66 in 23 osteolytic metastases, and 4.13±1.69 in 11 osteoblastic metastases (P<0.05). Conclusion 18F-FDG PET/CT is helpful to find the localization of unknown primary tumors in patients with bone metastases, and to make treatment Planning. Osteolytic metastases show higher metabolic activity on 18F-FDG PET/CT. |
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