边晓琳,张连仲,程兆云.实时三维超声心动图评价冠状动脉旁路移植术后左心室功能的逆转[J].中国医学影像技术,2009,25(4):613~616
实时三维超声心动图评价冠状动脉旁路移植术后左心室功能的逆转
Left ventricular function reverse remodeling evaluated with real-time three-dimensional echocardiography in patients with coronary artery bypass grafting
  
DOI:
中文关键词:  超声心动描记术,三维  冠状动脉分流术  心室重构
英文关键词:Echocardiography, three-dimensional  Coronary artery bypass  Ventricular remodeling
基金项目:
作者单位
边晓琳 郑州大学第一附属医院超声科,河南 郑州 450003 
张连仲 河南省人民医院超声科, 
程兆云 心外科,河南 郑州 450003 
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中文摘要:
       目的 探讨实时三维超声心动图(RT-3D)在评价冠状动脉旁路移植术后患者左心室功能。方法 选择经冠状动脉造影证实的三支冠状动脉病变患者20例作为冠心病组,无冠状动脉狭窄者20例作为正常对照组,应用RT-3D对冠心病组于术前3天及术后1个月测量左心室射血分数(EF),利用Qlab工作站自动生成的Excel表,手动计算峰值射血率(PER)、峰值充盈率(PFR)及基底段各壁局部峰值射血率、峰值充盈率,对照组测得EF、PER、PFR并与冠心病组术前比较。结果 与对照组比较,冠心病组术前左心室EF、PER、PFR减小,差异均有显著统计学意义(P<0.01);术后与术前比较,冠心病组左心室EF、PER、PFR显著增加(P<0.01),左心室基底段前壁、下壁、下侧壁、前侧壁PER、PFR增加(P<0.01),间隔壁无显著增加(P>0.05)。结论 冠心病患者左心室功能可发生重构,冠状动脉旁路移植术能逆转其重构,RT-3D可准确评价冠状动脉旁路移植术后患者左心室功能的逆转。
英文摘要:
      Objective To observe the value of real-time three-dimensional echocardiography (RT-3D) in evaluation of the left ventricular function reverse remodeling in patients with coronary artery disease (CAD) after coronary artery bypass grafting (CABG). Methods RT-3D were performed in 20 CAD patients with three-vessel stenosis and 20 people without coronary stenosis verified by coronary angiography. The left ventricular function parameters such as left ventricular ejection fraction (EF), the peak ejection rate (PER), peak filling rate (PFR) were obtained by Qlab software before CABG and 1 month after operation. EF, PER and PFR were compared between preoperative CAD group and normal control group. Results Compared with normal subjects, EF, PER and PFR in patients with CAD significantly decreased (P<0.01). The left ventricular EF, PER, PFR and basal regional PER, PFR increased (P<0.01) after operation except interventricular septum in CAD group (P>0.05). Conclusion Left ventricular function remodeling can take place in patients with CAD. CABG reverses LV function remodeling. The left ventricular function reverse remodeling can be evaluated with RT-3D in CAD patients after CABG.
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