| 梁国庆,姜铁民,赵季红,李学文,冯凯琳.64层螺旋CT与血管内超声虚拟组织学成像对冠状动脉斑块评估的对比观察[J].中国医学影像技术,2009,25(2):229~232 |
| 64层螺旋CT与血管内超声虚拟组织学成像对冠状动脉斑块评估的对比观察 |
| Comparative observation of coronary plaque with multi-slice computed tomography and intravascular ultrasound-virtual histology |
| 投稿时间：2008-07-23 修订日期：2008-12-10 |
| DOI： |
| 中文关键词: 冠状动脉 体层摄影术,X线计算机 粥样硬化斑块 |
| 英文关键词:Coronary artery Tomography, X-ray computed Atherosclerotic plaques |
| 基金项目: |
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| 摘要点击次数: 2011 |
| 全文下载次数: 787 |
| 中文摘要: |
| 目的 比较64层螺旋CT(MSCT)和血管内超声-虚拟组织学(IVUS-VH)技术对冠状动脉粥样斑块的的显示。方法 对30例患者行64层螺旋CT扫描后再行IVUS-VH检查。MSCT把冠状动脉斑块分为非钙化斑块、混合斑块、钙化斑块,并测量CT值。IVUS-VH把冠状动脉斑块成分分为:纤维斑块(F)、纤维脂质(FF)、钙化斑块(DC)和坏死核心(NC),分析相应的MSCT检查部位斑块的组成,同时评估TCFA斑块的发生率。结果 64层螺旋CT扫描发现101处斑块,28处(27.72%)为非钙化斑块;43处(42.57%)是混合斑块;30处(29.70%)是钙化斑块。非钙化斑块与钙化斑块相比含有较多的F(60.80%±9.19% vs 54.50%±8.28%,P<0.05)和FF(28.21%±13.01% vs 21.47%±9.78%,P<0.05)。混合斑块与钙化斑块和非钙化斑块相比含有较多的NC(11.12%±5.64% vs 8.21%±5.60%,P<0.05;13.75%±6.34% vs 8.21%±5.60%,P<0.01)和DC(7.71%±8.92% vs 2.78%±3.02%;10.28%±6.67% vs 2.78%±3.02%,P值均小于0.01)。混合斑块与非钙化斑块和钙化斑块相比TCFA发生率高(32.56%,10.71%,6.67%,P=0.007)。MSCT测量的钙化斑块CT值与IVUS-VH斑块成分中的DC成正相关(r=0.57, P＜0.001)。结论 MSCT测量的斑块CT值与IVUS-VH测量的斑块钙化百分比正相关。虽然IVUS-VH的分辨率高,但与MSCT检测到的斑块特性相似。MSCT检测的混合斑块与IVUS-VH的TCFA密切相关。 |
| 英文摘要: |
| Objective To compare the characteristics of the atherosclerotic plaques by multislice computed tomography (MSCT) and intravascular ultrasound-virtual histology(IVUS-VH). Methods A total of 30 patients underwent 64-slice MSCT followed IVUS-VH. Plaques were classified on MSCT as noncalcified, mixed and calcified, and the CT values were measured in coronary segments. Plaques were classified on IVUS-VH as fibrotic, fibro-fatty, necrotic core and dense calcium. The plaques were analyzed and the presence thin-cap fibroatheroma was evaluated. Results Totally 101 coronary plaques were evaluated as 28 (27.72%) noncalcified, 43 (42.57%) mixed and 30 (29.70%) calcified. Compared with calcified plaques, noncalcified plaques contained more fibrotic (P<0.05) and fibro-fatty (P<0.05) on IVUS-VH. Mixed and calcified plaques contained more necrotic core.Thin-cap fibroatheroma was most frequently observed in mixed plaques (P=0.007). A positively correlation was observed between the CT value by MSCT and calcium area on IVUS-VH (r=0.57, P＜0.001). Conclusion Positively correlation can be observed between the CT value by MSCT and calcified plaques area on IVUS-VH. Although IVUS-VH provides more precise plaque characterization, plaque classification on MSCT parallels relative plaque composition on IVUS-VH. Mixed plaques on MSCT is associated with high risk features on IVUS-VH. |
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