| 马隽,李吉,金银华,张霖,郝鑫,李志波,宋扬.1H-MRS鉴别脑膜瘤术后反应性损伤及残留与复发[J].中国医学影像技术,2005,21(7):1009~1012 |
| 1H-MRS鉴别脑膜瘤术后反应性损伤及残留与复发 |
| Role of 1H-MRS in differentiation residual/recurrent meningioma from non-neoplastic lesions |
| 投稿时间：2005-01-15 修订日期：2005-05-18 |
| DOI： |
| 中文关键词: 脑膜瘤 磁共振波谱学 磁共振成像 代谢 |
| 英文关键词:Meningioma Magnetic resonance spectroscopy Magnetic resonance imaging Metabolism |
| 基金项目: |
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| 摘要点击次数: 1582 |
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| 中文摘要: |
| 目的 探讨脑膜瘤术后的1H-MRS表现及其临床意义。方法 收集52例脑膜瘤病例,于术后7天、30天、3个月行增强MRI和1H-MRS检查,分析各种代谢物的变化。结果 在术后反应性强化组中,各代谢物与正常组织相比均无明显差异(P＞0.05)。在残留和复发的脑膜瘤中,各种代谢物术后不同时间、不同区域与正常组织相比均有显著性差异(P＜0.05)。结论 1H-MRS与增强MRI结合能提高对脑膜瘤术后反应性损伤与残留及复发鉴别诊断的准确性。 |
| 英文摘要: |
| Objective To evaluate the role of 1H-MRS in the differential diagnosis of residual/recurrent meningioma from non-neoplastic lesions. Methods Fifty-two patients with meningioma were collected. All patients underwent enhanced MRI and 1H-MRS respectively on the 7th, 30th day and 3rd month after the operation. Multivoxel proton MRS was performed on Toshiba ExcelARTTM 1.5T and diversified metabolite peaks were measured among different time and regions. Results No significant difference was found in the metabolic ratios of reactive enhanced region in different regions and time. NAA/Cho, NAA/Cr, Cho/ Cr, Ala, Glu, Lip and Lac showed significant difference in different regions and time after the operation in residual/recurrent meningioma (P<0.05). Conclusion 1H-MRS combined with enhanced MRI can improve diagnostic accuracy of differentiating residual/recurrent meningioma from non-neoplastic lesions. |
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