| 宋莉,王霄英,谢晟,肖江喜,蒋学祥.DWI以及ADC值测量在脑肿瘤鉴别诊断中的价值[J].中国医学影像技术,2005,21(3):354~357 |
| DWI以及ADC值测量在脑肿瘤鉴别诊断中的价值 |
| DWI and ADC value in differential diagnosis of brain tumors |
| 投稿时间：2004-09-19 修订日期：2004-12-06 |
| DOI： |
| 中文关键词: 弥散加权成像 表观弥散系数 磁共振成像 脑肿瘤 |
| 英文关键词:Diffusion weighted imaging Apparent diffusion coefficient Magnetic resonance imaging Brain tumors |
| 基金项目:本课题为国家自然科学基金资助项目(NO.10275003)。 |
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| 中文摘要: |
| 目的 探讨弥散加权成像以及表观弥散系数值测量在脑肿瘤鉴别诊断中的作用。方法 回顾性分析44例脑肿瘤的DWI与ADC值特点。结果 44例脑肿瘤表现分为如下五类:DWI高信号ADC值升高(n=19)、DWI高信号但ADC值减低(n=11)、DWI低信号ADC值升高(n=9)和DWI混杂信号ADC值升高(n=5)。转移瘤 、胶质瘤 及脑膜瘤 ADC值之间统计学差异不明显(F=3.47, P |
| 英文摘要: |
| Objective To evaluate the role of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) in the differential diagnosis of brain tumors. Methods MRI, using conventional and DWI, was performed in 44 patients with brain tumors using a 1.5 T MR scanner. ADC values were measured in the lesion and the coutralateral brain parenchyma. Results All gliomas, 3 meningiomas, 2 metastatic tumors, 1 cavernous hemangioma and 1 gangliocytoma were hyperintense on DWI with higher ADC than contralateral brain; 7 meningiomas, 2 metastatic tumors, 1 chloroma and 1 primary lymphoma in the brain were hyperintense on DWI with lower ADC; 4 metastatic tumors, 2 meningiomas, 2 hemangioblastomas and 1 cerebral cyst were hypointense on DWI with higher ADC than contralateral brain; 5 metastatic tumors depicted as mixed intense signal on DWI with higher ADC. The differences in mean ADC of metastasis , gliomas and meningiomas were not statistically significant (F=3.47, P>0.05). There was significant difference between the mean ADC of metastasis and that of the coutralateral brain (t=3.46, P=0.003); there was also significant difference between the mean ADC of gilomas and that of the coutralateral brain (t=3.88, P=0.001); there was no difference between the mean ADC of meningiomas and that of the coutralateral brain (t=0.62,P= 0.55). Conclusion DWI and ADC may evaluate brain tumors by providing the internal functional information, though ADC itself can not differentiate brain tumors. |
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