| 王金锐,王世宏,刘志跃,秦林金,杨海萍.应变积分曲线评价心梗病人左室局域舒张功能[J].中国医学影像技术,2002,18(11):1100~1102 |
| 应变积分曲线评价心梗病人左室局域舒张功能 |
| Evaluation of Regional Diastolic Function in Patients with Myocardial Infarction by Integrated Strain Curves |
| 投稿时间：2002-03-18 |
| DOI： |
| 中文关键词: 应变积分曲线 心肌梗死 舒张异常 局域心室 |
| 英文关键词:Integrated strain curve Myocardial infarction Diastolic abnormality Regional ventricle |
| 基金项目:本课题获内蒙古自治区自然科学基金资助(20001306)。 |
|
| 摘要点击次数: 1503 |
| 全文下载次数: 760 |
| 中文摘要: |
| 目的 探索冠心病(CAD)患者左室舒张各期局部心肌应变积分特点及其评价左室局域舒张功能的可能性。 方法 对18例前壁心肌梗死病人(MI组)和26例正常对照者(NOR组)记录心尖二腔动态组织多普勒图像,应用应变积分曲线(ISC)描记技术获取左室各节段心肌长轴方向的同步应变积分曲线,测量等容舒张期(IR)、快速充盈期(RF)、缓慢充盈期(SF)和心房收缩期(AC)的时间、应变积分值(IS)及变化幅度。对两组结果进行对比分析。 结果 在正常组舒张各期,22/26(84.62％)例,按前壁心尖、心底、中部的顺序,IS呈负值增大梯度变化;心梗病人符合这一规律仅3/18(16.67%)例。IR期:NOR组188/208(90.38%)节段,为向上波段且走行较一致;MI组向上波段有41/144(28.47%)节段,且各节段波走行不一致, 两组相比,P<0.05。RF期:NOR组多为快速向上波段(192/208节段,92.31%);MI组向上波段少(34/144节段,23.61%)两组相比,P<0.01。 SF期:与NOR组多为水平波段相比,MI组在缺血节段多为向上波段,P<0.05。 结论 局部心肌缺血梗死导致主动舒张期沿长轴方向的局部心肌应变积分显著异常。应变积分能敏感、直观地无创定量评价局域心肌舒张功能异常;对早期诊断冠心病心肌缺血,阐明心室重构的机制可能有重要价值。 |
| 英文摘要: |
| Objective To detect the integrated strain features of regional wall abnormalities in patients with coronary artery disease (CAD) during each diastolic period,and its possibility to evaluate regional left ventricular diastolic function. Methods Eighteen patients with anterior myocardial infarction(MI group)and 26 normal subjects(NOR group)underwent Doppler tissue imaging, which was performed in apical 2-chamber-view. Integrated strain of LV segments along long axis and time during each diastolic period were analyzed by off-line integrated strain curves synchronously. Results In NOR group, 22/26 (84.62%) cases had IS showings with a trend of gradually increasing negative value from apex to base to middle of left ventricle, while in MI group, there were 3/18 (16.67%) cases with such a trend. In NOR group, 188/208 (90.38%) segments during IR phase were upward wave bands, but in MI group, there were 41/144 (28.47%) segments having such waves, P<0.05. RF phase: in NOR group, 192/208 (92.31%) segments were upward and steep wave bands, but in MI group, the number of upward waves were obviously less (34/144 segments, 23.61%) (P<0.01). SF phase: compared with NOR group which was horizontal, MI group had upward wave bands, P<0.05. Conclusion Regional myocardial ischemia and infarction can cause significant regional diastolic wall abnormalities of integrated strain in active diastolic phase. Regional diastolic wall motion abnormalities can be evaluated quantitatively and synchronously with high sensitivity by ISC which has the potential value in early diagnosis of regional myocardial ischemia in CAD and clarifying the mechanism of ventricular reconstruction. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
