詹淑琴,贾建平,王默力,于跃怡.POEMS综合征合并急性脑梗塞[J].中国医学影像技术,2002,18(1):30~31
POEMS综合征合并急性脑梗塞
Acute Cerebral Infarction in POEMS Syndrome
投稿时间:2001-10-28  
DOI:
中文关键词:  POEMS综合征  脑梗塞
英文关键词:POEMS syndrome  Cerebral infarction
基金项目:
作者单位
詹淑琴 首都医科大学宣武医院神经内科,北京 100053 
贾建平 首都医科大学宣武医院神经内科,北京 100053 
王默力 首都医科大学宣武医院神经内科,北京 100053 
于跃怡 首都医科大学宣武医院神经内科,北京 100053 
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中文摘要:
      目的 观察和探讨POEMS综合征与急性脑梗塞的内在相关性。方法 报道1例确诊为POEMS综合征的男性病人,在病后半年突然出现左侧肢体完全偏瘫,通过对临床、血液有形成分、电生理及影像学进行研究。结果 血红细胞、血红蛋白、血小板计数及血细胞压积明显增高,肌电图显示广泛神经传导速度减慢,骨盆片可见骨硬化病灶,头颅MRI显示右侧大脑颞、额、顶、枕大面积脑梗塞。结论 POEMS综合征可以引起广泛的血管病变包括大血管、中小血管及毛细血管,成为导致血管闭塞的直接原因,而微血管病变可能在 POEMS综合征的发病机制中起重要作用。
英文摘要:
      Objective To observe and study the relationship between acute cerebral infarction and POEMS syndrome. Methods Fourty four-year-old man with typical POEMS syndrome developed acute cerebral thrombosis next 6 months after diagnosis. Clinical, blood cell, electrophysiological and radiological manifestations were studied. Results The blood red cell, hematoglobin, platelet counts were elevated. Electromyograph finding revealed that motor and sensory conduction velocity was reduced, radiograph of pelvis showed osteosclerotic lesion. MRI examination showed a large ischemic area of in right cerebrosphere. Conclusion Vasculature of various sizes are affected in POEMS syndrome. Vaculopathy may be important in the pathogenesis of POEMS syndrome.
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