何文,谭杰琳,姜晓红,徐利群,郑永才.超声引导热化疗介入治疗肝癌的临床研究[J].中国医学影像技术,2001,17(10):929~930
超声引导热化疗介入治疗肝癌的临床研究
Clinical Study of US-Guided Thermochemotherapy in the Treatment of Liver Cancer
投稿时间:2001-06-02  
DOI:
中文关键词:  肝肿瘤  热化疗  介入性超声  5-FU
英文关键词:Liver neoplamas  Thermochemotherapy  Interventional ultrasonography  5-FU
基金项目:
作者单位
何文 首都医科大学附属北京朝阳医院超声科,北京 100020 
谭杰琳 广西柳州市人民医院超声科 
姜晓红 首都医科大学附属北京朝阳医院超声科,北京 100020 
徐利群 首都医科大学附属北京朝阳医院超声科,北京 100020 
郑永才 首都医科大学附属北京朝阳医院超声科,北京 100020 
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中文摘要:
      目的 探讨超声引导下热化疗介入肝癌的可行性和疗效。方法 48例肝癌患者,超声引导下 20G穿刺针穿入肿瘤内,5-FU加热到80℃后,3min内注完 5-FU 250~1500mg。与同期18例超声引导瘤内注射化疗药比较。结果 治疗后肿瘤均有不同程度缩小,境界清晰,内部回声增强。肿瘤缩小率48.6%±7.16%,同期瘤内注射化疗药肿瘤缩小率29.0%±9.21%,差异有显著性(P<0.05)。结论 本方法简便易行,是一种治疗肝癌的可行性方法。
英文摘要:
      Objective To evaluate the feasibility and effect of US-guided thermochemotherapy in the treatment of hepatic carcinoma. Methods 48 cases of hepatic cancer were treated with thermochemotherapy, by US-guided,with 5-FU warmed to 80℃ before infusion into hepatic cancer. The effectiveness was compared with those of 18 patients receiving chemotherapy by US-guided within the same period. Results 34 patients remained alive in 3-60 months.After the treatment, all lesions(nodules) were decreased in size and blood flow in nodules disappeared. The tumor decrease rate of thermochemotherapy group was 48.6%±7.16% while that of the control group was 29.0%±9.21%,showing statistically significant difference. MConclusion US-guided thermochemotherapy is a simple,effective, safe method in the treatment of liver cancer.
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