| 孟庆杨,马淑梅,樊海宁,乔志忠,李晓君.实时剪切波弹性成像在肝泡型包虫病与肝细胞性肝癌中的鉴别诊断价值[J].中国医学影像技术,2020,36(1): |
| 实时剪切波弹性成像在肝泡型包虫病与肝细胞性肝癌中的鉴别诊断价值 |
| Clinical research of real-time shear wave elastography in differential diagnosis of hepatic alveolar echinococcosis and hepatocellular carcinoma |
| 投稿时间：2019-04-26 修订日期：2020-01-13 |
| DOI： |
| 中文关键词: 剪切波弹性成像 肝泡型包虫病 肝细胞性肝癌 ROC曲线 |
| 英文关键词:shear-wave elastography Hepatic alveolar echinococcosis Hepatocellular Carcinoma ROC curve |
| 基金项目:]：青海省科技厅重大科技专项 (2016-SF-A5),青海省卫计委课题(2016-wjzd-04)。 |
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| 中文摘要: |
| [摘要] 目的 通过研究实时剪切波弹性成像（SWE）在肝泡型包虫病(HAE)与肝细胞性肝癌（HCC）的弹性特征，从而探讨SWE在HAE与HCC鉴别诊断中的临床应用价值。 方法 随机收集20例HAE及30例HCC患者的肝脏占位病灶，术前对所有患者的病灶进行SWE检查，获取所有病灶的平均杨氏模量值，所有病灶均以病理结果为金标准，对SWE在HAE与HCC鉴别诊断的效能及准确性进行评价。 结果 HAE组平均杨氏模量值为（34.57±10.76）Kpa,HCC组平均杨氏模量值为（21.82±3.51）Kpa，差异具有统计学意义（P<0.001）.通过构建ROC曲线确定HAE及HCC平均杨氏模量值的诊断界值为27.43Kpa，其敏感度为80.00%、特异度为97.00%,曲线下面积为86.90%。 结论 SWE在HAE和HCC鉴别诊断中具有重要的临床应用价值。 |
| 英文摘要: |
| [Abstract] Objective To evaluate the elastic characteristics of real-time shear wave elastography (SWE) in patients with hepatic alveolar echinococcosis (HAE) and hepatocellular carcinoma (HCC) and investigate the clinical application of SWE in differential diagnosis of HAE and HCC. Methods There were 20 cases in the HAE group and 30 cases in the HCC group in the study.All the cases were performed SWE before surgery,the mean elasticity of Young’s modulus of all the cases were obtained.All the lesions were conformed by pathologies as the gold standard.SWE results were compared with the pathologies to evaluate the accuracy and efficacy of using SWE to diagnose the HAE and HCC. Results The mean elasticity of Young’s modulus of the lesions was （34.57±10.76）Kpa in the HAE group and （21.82±3.51) Kpa in the HCC group.The mean elasticity of Young’s modulus of lesions had significant difference between HAE and HCC groups (P<0.001).The critical point of the mean elasticity of Young’s modulus of the lesions between HAE and HCC was 27.43Kpa by ROC curve,the sensitivity was 80% ,and the specificity was 97%.The area under the ROC curve was 86.9%. Conclusion SWE has an important value of clinical application in diagnosis between HAE and HCC. |
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