| 赵国瑞,高超,赵岩,闫淑坤,曹绍东.深度学习重建用于低剂量冠状动脉CT血管成像[J].中国医学影像技术,2026,42(6):957~962 |
| 深度学习重建用于低剂量冠状动脉CT血管成像 |
| Deep learning reconstruction of low-dose coronary CT angiography |
| 投稿时间：2025-11-24 修订日期：2026-06-17 |
| DOI：10.13929/j.issn.1003-3289.2026.06.034 |
| 中文关键词: 冠状血管 体层摄影术,X线计算机 深度学习 |
| 英文关键词:coronary artery tomography, X-ray computed deep learning |
| 基金项目: |
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| 摘要点击次数: 172 |
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| 中文摘要: |
| 目的 观察深度学习(DL)重建用于低剂量冠状动脉CT血管成像(CCTA)的价值。方法 前瞻性纳入120例拟接受CCTA检查的疑诊冠心病患者并分为A~D组(n=30),A组管电压120 kVp、管电流160 mAs,B~D组管电压100 kVp,自动管电流调制技术,预设图像质量水平依次为1.3、1.0及0.7。分别以滤波反投影(FBP)、60% Clear View+混合迭代及60% Clear Infinity DL重建图像,记为A1~D1、A2~D2及A3~D3亚组。比较组内各亚组间和B3、C3、D3亚组与A2亚组图像质量的主、客观评价结果,以及A~D组辐射剂量。结果 各组内A3、B3、C3、D3亚组主观评分最高(P均＜0.05);B3、C3、D3亚组主观评分均高于A2亚组(P均＜0.05)。A3亚组主动脉根部、左主干(LM)、左前降支(LAD)、左回旋支(LCX)及右冠状动脉(RCA)处信噪比(SNR)及对比度噪声比(CNR)均高于A1、A2亚组(P均＜0.05);B3亚组主动脉根部、LM、LAD、LCX及RCA处SNR及CNR均高于B1、B2亚组(P均＜0.05);除LAD SNR与C1亚组差异无统计学意义(P＞0.05)外,C3亚组上述血管处SNR及CNR均高于C1、C2亚组(P均＜0.05);除主动脉根部SNR与D1亚组差异无统计学意义(P＞0.05)外,D3亚组上述血管处SNR及CNR均高于D1、D2亚组(P均＜0.05)。B3、D3亚组主动脉根部、LAD、LCX及RCA处SNR及CNR均高于A2亚组,C3亚组LAD、LCX及RCA处SNR均高于A2亚组(P均＜0.05)。相比A组,B~D组有效剂量分别降低72.82%、82.72%及90.69%。结论 DL重建有助于提高低剂量CCTA图像质量。 |
| 英文摘要: |
| Objective To observe the value of deep learning (DL) reconstruction of low-dose coronary CT angiography (CCTA). Methods Totally 120 patients with suspected coronary heart disease who would undergo CCTA were prospectively enrolled and divided into groups A—D (each n=30) . CCTA with tube voltage 120 kVp and tube current 160 mAs was performed in group A, while with tube voltage 100 kVp, automatic tube current modulation and preset image quality level of 1.3, 1.0, and 0.7 was performed in groups B—D, respectively. Four sets of images were reconstructed in each group using filtered back projection (FBP), 60% Clear View + hybrid iterative and 60% Clear Infinity DL reconstruction, named subgroups A1—D1, A2—D2, and A3—D3. Subjective scores and objective evaluation results were compared among subgroups within groups and subgroups A2, B3, C3 and D3, while radiation dose was compared among groups. Results Subgroups A3, B3, C3, D3 had the highest subjective scores in groups A—D, respectively (all P＜0.05). Subjective scores of subgroups B3, C3 and D3 were all higher than that of subgroup A2 (all P＜0.05). Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) at the aortic root, left main coronary artery (LM), left anterior descending artery (LAD), left circumflex artery (LCX) and right coronary artery (RCA) in subgroup A3 were higher than those in subgroups A1 and A2 (all P＜0.05). SNR and CNR at the aortic root, LM, LAD, LCX and RCA in subgroup B3 were higher than those in subgroups B1 and B2 (all P＜0.05). In group C, LAD SNR showed no significant difference between subgroup C3 and subgroup C1 (P＞0.05), while SNR and CNR of the above mentioned vessels in subgroup C3 were higher than those in subgroups C1 and C2 (all P＜0.05). In group D, aortic root SNR showed no significant difference between subgroup D3 and subgroup D1 (P＞0.05), while SNR and CNR values of all above mentioned vessels in subgroup D3 were higher than those in subgroups D1 and D2 (all P＜0.05). SNR and CNR of aortic root, LAD, LCX and RCA in subgroups B3 and D3 were all higher than those in subgroup A2, SNR of LAD, LCX and RCA in subgroup C3 were all higher than those in subgroup A2 (all P＜0.05). Compared with group A, effective dose of groups B to D decreased by 72.82%, 82.72% and 90.69%, respectively. Conclusion DL reconstruction helped to improve imaging quality of low-dose CCTA. |
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