| 李元子,葛辉玉,刘心娟,林琳,王斯宇,张丽,孙家宝.多模态超声检查评估炎性肠病活动性[J].中国医学影像技术,2026,42(6):881~885 |
| 多模态超声检查评估炎性肠病活动性 |
| Multimodal ultrasound for evaluating activity of inflammatory bowel diseases |
| 投稿时间：2025-11-30 修订日期：2026-04-12 |
| DOI：10.13929/j.issn.1003-3289.2026.06.015 |
| 中文关键词: 炎性肠病 疾病活动性 显微超声造影 |
| 英文关键词:inflammatory bowel diseases disease activity super resolution contrast-enhanced ultrasound |
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| 中文摘要: |
| 目的 探讨利用多模态超声检查评估炎性肠病(IBD)活动性的可行性。方法 回顾性分析接受常规肠道超声及肠镜检查的51例IBD患者,其中26例同期接受超声造影(CEUS)、10例同期接受SR CEUS检查。根据内镜所见划分活动期组(n=42)与缓解期组(n=9);对比组间常规超声表现和CEUS及SR CEUS参数,分析SR CEUS参数[血管密度(VD)、血流容积(FWVD)、分形维数(FD)]与病变Limberg血流信号分级的相关性。结果 活动期组常规超声所示肠壁厚度、Limberg 3~4级血流信号占比(P均＜0.001),以及CEUS显示上升支斜率与峰值强度(P均<0.05),SR CEUS显示VD和FWVD均高于缓解期组(P均＜0.05)。VD、FWVD及FD均与病变Limberg血流分级呈正相关(ρ=0.763、0.909、0.720,P均＜0.05)。结论 利用多模态超声可评估IBD活动性;SR CEUS参数VD与FWVD对于鉴别IBD活动性具有潜在价值。 |
| 英文摘要: |
| Objective To explore the feasibility of multimodal ultrasound for evaluating activity of inflammatory bowel diseases (IBD). Methods Data of 51 IBD patients who underwent conventional intestinal ultrasound and colonoscopy were retrospectively analyzed, including 26 patients who underwent contrast-enhanced ultrasound (CEUS) and 10 patients who underwent super resolution contrast-enhanced ultrasound (SR CEUS). The patients were divided into active group (n=42) and remission group (n=9) according to endoscopic findings. Then conventional ultrasonic manifestations and parameters of CEUS and SR CEUS were compared between groups, and the correlations of SR CEUS parameters (vessel density [VD], flow-weighted vessel density, fractal dimension) with Limberg grading of IBD lesions were explored. Results The thickness of the involved intestinal wall and the proportion of Limberg 3—4 blood flow signal showed in conventional ultrasound in active group were both larger than those in remission group (both P＜0.001). The ascent slope of the rising branch and peak intensity in CEUS in active group were both higher than those in remission group (both P＜0.05). VD and FWVD in SR CEUS in active group were both higher than those in remission group (both P＜0.05). VD, FWVD and FD were all positively correlated with Limberg grading (ρ=0.763, 0.909, 0.720, all P＜0.05). Conclusion Multimodal ultrasound could be used to evaluate the activity of IBD. Parameters of SR CEUS, i.e. VD and FWVD had potential value for evaluating the activity of IBD. |
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