| 王舒婷,刘俊刚,饶志远,黄炳旭,施明慧,潘世强,肖珩珂,蒋中臻,王健.非镇静干预用于改善学龄前儿童颅脑MR成像质量[J].中国医学影像技术,2026,42(3):434~438 |
| 非镇静干预用于改善学龄前儿童颅脑MR成像质量 |
| Non-sedative intervention for improving imaging quality of cranial MR in preschool children |
| 投稿时间：2025-02-18 修订日期：2025-09-02 |
| DOI：10.13929/j.issn.1003-3289.2026.03.023 |
| 中文关键词: 儿童 脑 磁共振成像 前瞻性研究 |
| 英文关键词:child brain magnetic resonance imaging prospective studies |
| 基金项目:厦门市科技计划项目(3502Z20199096)。 |
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| 摘要点击次数: 60 |
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| 中文摘要: |
| 目的 观察非镇静干预用于改善学龄前儿童颅脑MR成像质量的价值。方法 前瞻性纳入144例将接受颅脑MR检查患儿,根据是否需要镇静分为非镇静组(n=62)与镇静组(n=82)。分别选取脑干、小脑白质、额叶皮层、枕叶皮层、尾状核头、半卵圆中心、胼胝体膝部、胼胝体压部、脑脊液及背景共10个ROI,测量其信号强度,计算图像信噪比(SNR)。比较组间MR T1WI、T2WI及T2-液体衰减反转恢复(FLAIR)图像主观评分和客观评价结果;观察非镇静组内不同性别患儿客观指标差异,分析客观指标与年龄的相关性。结果 观察者间图像质量评分的一致性较好(Kappa=0.78,P＜0.05)。组间各序列灰白质界面清晰度评分差异均无统计学意义(P均＞0.05)。非镇静组T1WI及T2WI伪影评分1级者占比低于镇静组(P均＞0.05);T2-FLAIR伪影评分组间差异无统计学意义(P＞0.05)。非镇静组T2WI大脑灰质、脑脊液及脑干SNR均低于镇静组(Z=-2.833、-3.111、-3.990,P均＜0.05),组间其余客观指标差异均无统计学意义(P均＞0.05)。非镇静组不同性别间客观指标差异均无统计学意义(P均＞0.05);T2WI脑干SNR与年龄呈弱正相关(rS=0.255,P=0.045),其余指标与年龄无明显相关(P均＞0.05)。结论 非镇静干预有助于改善学龄前儿童颅脑MR成像质量。 |
| 英文摘要: |
| Objective To observe the value of non-sedative intervention for improving imaging quality of cranial MR in preschool children. Methods A total of 144 pediatric patients who would underdo cranial MR examination were prospectively enrolled and divided into non-sedation group (n=62) and sedation group (n=82) according to whether needing sedation. ROI was selected in brainstem, cerebellar white matter, frontal cortex, occipital cortex, head of the caudate nucleus, centrum semiovale, genu of the corpus callosum, splenium of the corpus callosum, cerebrospinal fluid and background, respectively. The signal intensity of each ROI was measured, and image signal-to-noise ratio (SNR) was calculated. The subjective scores and objective evaluations of MR T1WI, T2WI and T2-fluid attenuated inversion recovery (FLAIR) were compared between groups, the differences of objective indicators in non-sedation group were analyzed between different genders, and the correlations of objective indicators with age were observed. Results The inter-observer consistency of imaging quality scores was good (Kappa=0.78, P＜0.05). No significant difference of clarity score of gray white matter interface in each sequence was found between groups (all P＞0.05). The proportion of ones with grade 1 T1WI and T2WI artifact scores in non-sedation group were lower than in sedation group (both P＞0.05), while no significant difference of T2-FLAIR artifact scores was observed between groups (P＞0.05). In T2WI, SNR of gray matter, cerebrospinal fluid and brainstem of non-sedation group were lower than those of sedation group (Z=-2.833, -3.111, -3.990, all P＜0.05), while no significant difference of other objective indicators was detected between groups (all P＞0.05). There was no significant difference of objective indicators between different genders in non-sedation group (all P＞0.05). SNR of brainstem in T2WI showed a weak positive correlation with patient's age (rS=0.255, P=0.045), while other indicators showed no significant correlation with age (all P＞0.05). Conclusion Non-sedative intervention was helpful to improving imaging quality of cranial MR in preschool children. |
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