| 柯淑君,徐化凤.儿童睾丸间质细胞瘤临床及影像学表现[J].中国医学影像技术,2026,42(3):399~402 |
| 儿童睾丸间质细胞瘤临床及影像学表现 |
| Clinical and imaging manifestations of Leydig cell tumor in children |
| 投稿时间：2025-12-23 修订日期：2026-03-12 |
| DOI：10.13929/j.issn.1003-3289.2026.03.016 |
| 中文关键词: 儿童 睾丸间质细胞瘤 磁共振成像 超声检查 |
| 英文关键词:child Leydig cell tumor magnetic resonance imaging ultrasonography |
| 基金项目: |
|
| 摘要点击次数: 71 |
| 全文下载次数: 29 |
| 中文摘要: |
| 目的 观察儿童睾丸间质细胞瘤(LCT)的临床及影像学表现。方法 回顾性分析5例经手术病理证实的LCT患儿的临床、MRI及超声资料,观察肿瘤侧别、大小、形态、边界、信号/回声及强化表现等。结果 5例患儿月龄30~151个月,临床表现包括睾丸肿大、睾丸内肿块及性早熟;术前睾酮升高4例、催乳素升高2例,神经元特异性烯醇化酶升高4例;5例均接受睾丸肿瘤剜除术,术后病理报告均为良性。影像学显示5例均为单发LCT,位于左侧4例、右侧1例,肿瘤边界清楚、轮廓光整,长径0.5~1.2 cm。MRI显示4例肿瘤信号均匀、1例欠均匀,T1WI均呈稍高信号、T2WI均呈低信号,弥散加权成像中肿瘤均未见弥散受限,亦未见出血及囊变;增强扫描5例均见强化,4例呈不均匀强化、1例均匀强化,包括3例中度强化、2例轻度强化。超声显示睾丸内不均质结节,4例呈混合回声、1例呈低回声;CDFI均于其内见丰富血流信号。结论 儿童LCT临床及影像学表现具有一定特征性;结合临床有助于提高诊断准确率。 |
| 英文摘要: |
| Objective To observe the clinical and imaging manifestations of pediatric Leydig cell tumors (LCT). Methods Clinical, MRI and ultrasound data of 5 children with LCT confirmed by surgical pathology were retrospectively analyzed. The laterality, size, shape, contour and margin of lesions, MRI signals/ultrasound echogenicities and enhancement were analyzed. Results The ages of 5 children ranged from 30 to 151 months. Clinical manifestations mainly included testicular enlargement, testicular masses and precocious puberty, as well as elevated testosterone in 4 cases, elevated prolactin in 2 cases and elevated neuron-specific enolase in 4 cases. All 5 children underwent testicular tumor excision, and pathological examination showed benign tumors in all 5 cases. The tumor presented as solitary lesion in all 5 cases, 4 located in the left testis and 1 in the right, with clear margins, smooth contours, and relatively small volumes with long diameter ranged from 0.5 to 1.2 cm. On MRI, 4 tumors showed uniform signals and 1 tumor showed slightly non-uniform signal, with slightly high signals on T1WI, low signals on T2WI, but no restricted diffusion on diffusion weighted imaging. No bleeding or cystic necrosis was observed inside tumors. On contrast-enhanced MRI, tumor enhancement was noticed in all 5 cases, including inhomogeneous enhancement in 4 cases and homogeneous enhancement in 1 case, presenting as moderate enhancement in 3 cases and mild enhancement in 2 cases. Gray-scale ultrasound revealed heterogeneous nodules within testis, 4 with mixed and 1 with low echogenicities. CDFI showed abundant blood flow signals within the tumors in all 5 cases. Conclusion Clinical and imaging manifestations of pediatric LCT had certain characteristics. Combining with clinic could improve diagnostic accuracy. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
