| 兰俊杰,邓杰,邱丽华.基于静息态功能MRI研究不同运动亚型帕金森病脑功能连接进展[J].中国医学影像技术,2025,41(10):1755~1758 |
| 基于静息态功能MRI研究不同运动亚型帕金森病脑功能连接进展 |
| Research progresses of resting-state functional MRI for brain functional connectivity in Parkinson disease motor subtypes |
| 投稿时间:2025-03-10 修订日期:2025-07-17 |
| DOI:10.13929/j.issn.1003-3289.2025.10.032 |
| 中文关键词: 帕金森病 磁共振成像 功能性神经影像学 |
| 英文关键词:Parkinson disease magnetic resonance imaging functional neuroimaging |
| 基金项目:国家重点研发计划(2022YFC2009901、2022YFC2009900)。 |
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| 中文摘要: |
| 帕金森病(PD)可根据运动症状而分为震颤为主(TD)、姿势不稳/步态障碍(PIGD)及少动-强直(AR)三种主要亚型。静息态功能MRI(rs-fMRI)通过分析脑功能连接(FC)而为阐释PD神经机制提供了新的视角。本文就rs-fMRI研究不同运动亚型PD FC进展进行综述。 |
| 英文摘要: |
| Parkinson disease (PD) can be classified into tremor-dominant (TD), postural instability gait difficulty (PIGD) and akinetic-rigid (AR) subtypes according to motor symptoms. Resting-state functional MRI (rs-fMRI) provided a new perspective to elucidate the neural mechanisms of PD through analyzing functional connectivity (FC) of the brain. The research progresses of rs-fMRI for FC in different motor subtype of PD were reviewed in this article. |
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