| 胡献阔,张杨,袁玉山,张磊,马培旗,李小虎.舌下含服硝酸甘油对无对比剂MR冠状动脉血管成像效果的影响[J].中国医学影像技术,2025,41(10):1730~1734 |
| 舌下含服硝酸甘油对无对比剂MR冠状动脉血管成像效果的影响 |
| Impact of sublingual nitroglycerin on imaging quality of non-contrast MR coronary angiography |
| 投稿时间：2025-03-19 修订日期：2025-10-01 |
| DOI：10.13929/j.issn.1003-3289.2025.10.027 |
| 中文关键词: 冠心病 冠状动脉血管造影术 磁共振成像 硝酸甘油 前瞻性研究 |
| 英文关键词:coronary disease coronary angiography magnetic resonance imaging nitroglycerin prospective studies |
| 基金项目:阜阳市自筹经费科技计划项目(FK202081049)、阜阳市卫生健康委科研项目(FY2021-011)。 |
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| 中文摘要: |
| 目的 观察舌下含服硝酸甘油(NTG)对无对比剂MR冠状动脉血管成像(NMRCA)效果的影响。方法 前瞻性纳入30例拟接受冠状动脉(CA)造影(CAG)检查的疑诊冠心病(CHD)患者,分别于舌下含服NTG前、后采集NMRCA图像,将CAG显示管腔狭窄≥50％判定为有临床意义狭窄,比较2种图像质量评分、CA内径及其可见长度,以及含服NTG对于NMRCA诊断CA狭窄效能的影响。结果 含服NTG后,左主干(LM)-左前降支(LAD)和左回旋支(LCX),以及LAD近段、中段、远段和LCX远段图像质量均有明显改善(P均＜0.05)。含服NTG前、后各支CA可见长度差异均无统计学意义(P均＞0.05)。含服NTG后右冠状动脉(RCA)、LM-LAD及LCX直径均较前增加(P均＜0.05),增幅分别为16.23%(13.57%,19.17%)、17.52%(12.69%,21.11%)及14.30%(7.62%,23.22%);且NMRCA诊断各支CA及其各节段狭窄的敏感度、特异度、准确率及阴性预测值均较前提高(P均＜0.05)。结论 舌下含服NTG可改善NMRCA图像质量、提高其诊断冠状动脉狭窄的效能。 |
| 英文摘要: |
| Objective To observe the impact of sublingual nitroglycerin (NTG) on imaging quality of non-contrast MR coronary angiography (NMRCA). Methods Thirty patients with suspected coronary heart disease (CHD) who would undergo coronary angiography (CAG) examination were prospectively collected. NMRCA images were acquired before and after sublingual NTG. Clinical meaningful stenosis was defined as CAG showed luminal stenosis ≥50%. Then imaging quality scores, diameters and display length of coronary arteries, as well as the impact of NTG on diagnostic performances of NMRCA for coronary artery stenosis were compared between images before and after administration of NTG. Results After administration of NTG, image quality of left main (LM)-left anterior descending artery (LAD) and left circumflex artery (LCX), as well as the proximal, mid and distal segments of LAD and distal segment of LCX significantly improved (all P＜0.05). No significant difference of visible coronary artery length was noticed before and after administration of NTG (all P＞0.05). After administration of NTG, diameter of right coronary artery (RCA), LM-LAD and LCX increased (all P＜0.05), with dilation rate of 16.23% (13.57%, 19.17%), 17.52% (12.69%, 21.11%) and 14.30% (7.62%, 23.22%), respectively, while the sensitivity, specificity, accuracy and negative predictive value of NMRCA for diagnosing coronary artery stenosis improved (all P＜0.05). Conclusion Sublingual NTG could improve imaging quality of NMRCA and increase its efficacy for diagnosing coronary artery stenosis. |
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