| 林晗,周姣.18F-FDG PET/CT鉴别肠弥漫性大B细胞淋巴瘤与肠腺癌[J].中国医学影像技术,2025,41(10):1691~1695 |
| 18F-FDG PET/CT鉴别肠弥漫性大B细胞淋巴瘤与肠腺癌 |
| 18F-FDG PET/CT for distinguishing intestinal diffuse large B-cell lymphoma and intestinal adenocarcinoma |
| 投稿时间：2024-12-13 修订日期：2025-06-10 |
| DOI：10.13929/j.issn.1003-3289.2025.10.018 |
| 中文关键词: 肠肿瘤 淋巴瘤,大B细胞,弥漫性 腺癌 正电子发射断层显像 诊断,鉴别 |
| 英文关键词:intestinal neoplasms lymphoma, large B-cell, diffuse adenocarcinoma positron-emission tomography diagnosis, differential |
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| 中文摘要: |
| 目的 观察18F-FDG PET/CT鉴别肠弥漫性大B细胞淋巴瘤(DLBCL)与肠腺癌的价值。方法 回顾性纳入经病理确诊的31例肠DLBCL(DLBCL组)及60例肠腺癌(腺癌组)患者,以单因素及多因素logistic回归分析18F-FDG PET/CT资料,包括病变PET/CT表现及18F-FDG代谢参数 ,筛选肠DLBCL与肠腺癌的独立鉴别因素并构建回归模型,评估其拟合度;分析各单一独立鉴别因素及回归模型鉴别肠DLBCL与肠腺癌的效能。结果 组间病变数目、累及部位、受累肠管长度及18F-FDG代谢参数差异均有统计学意义(P均＜0.05)。病变数目、累及肠管长度及SUVmax均为肠DLBCL与肠腺癌的独立鉴别因素(P均＜0.05),以之构建的回归模型拟合度佳(P=0.502);基于病变数目、受累肠管长度、SUVmax及回归模型鉴别肠DLBCL与肠腺癌的曲线下面积分别为0.732、0.838、0.755及0.889。结论 18F-FDG PET/CT可有效鉴别肠DLBCL与肠腺癌。 |
| 英文摘要: |
| Objective To explore the value of 18F-FDG PET/CT for distinguishing intestinal diffuse large B-cell lymphoma (DLBCL) and intestinal adenocarcinoma. Methods A total of 31 patients with intestinal DLBCL (DLBCL group) and 60 patients with intestinal adenocarcinoma (adenocarcinoma group) diagnosed by pathology were retrospectively enrolled. Univariate and multivariate logistic regression were used to analyze 18F-FDG PET/CT data, including lesions’ PET/CT manifestations and 18F-FDG metabolic parameters (the maximum standard uptake value , mean standard uptake value , metabolic tumor volume and total lesion glycolysis ), in order to screen out the independent differentiating factors for intestinal DLBCL and intestinal adenocarcinoma, based on which then a regression model was constructed, and its goodness of fit was evaluated. The efficacy of each single independent differentiating factor and the regression model for distinguishing intestinal DLBCL and intestinal adenocarcinoma were analyzed. Results Significant differences of lesion’s number, involved sites, involved intestinal length and 18F-FDG metabolic parameters were found between groups (all P＜0.05). The number of lesions, involved intestinal length and lesions’ SUVmax were all the independent differentiating factors for intestinal DLBCL and intestinal adenocarcinoma (all P＜0.05), and the regression model constructed based on the above factors had a good fit (P=0.502). The area under the curve for distinguishing intestinal DLBCL and intestinal adenocarcinoma based on lesions’ number, the involved intestinal length, SUVmax and the regression model was 0.732, 0.838, 0.755 and 0.889, respectively. Conclusion 18F-FDG PET/CT could effectively distinguish intestinal DLBCL and intestinal adenocarcinoma. |
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