| 贾楠,韩露,董越,刘冠宇,罗娅红.基于动态增强MRI Node-RADS评估乳腺癌腋窝淋巴结转移[J].中国医学影像技术,2025,41(10):1672~1676 |
| 基于动态增强MRI Node-RADS评估乳腺癌腋窝淋巴结转移 |
| Node-RADS based on dynamic contrast-enhanced MRI for evaluating axillary lymph node metastasis of breast cancer |
| 投稿时间：2024-12-25 修订日期：2025-06-18 |
| DOI：10.13929/j.issn.1003-3289.2025.10.014 |
| 中文关键词: 乳腺肿瘤 淋巴转移 磁共振成像 |
| 英文关键词:breast neoplasms lymphatic metastasis magnetic resonance imaging |
| 基金项目:辽宁省科学技术计划项目(2024-MSLH-278、2024JH2/102600185)、沈阳市科技计划项目(24-214-3-172)。 |
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| 中文摘要: |
| 目的 观察基于动态增强MRI(DCE-MRI)淋巴结报告和数据系统(Node-RADS)评估乳腺癌腋窝淋巴结转移的价值。方法 回顾性分析308例乳腺癌,根据有无腋窝淋巴结转移将其分为转移组(n=153)与非转移组(n=155);由2名医师根据Node-RADS评分标准分别对DCE-MRI所示腋窝淋巴结进行评分,采用Kappa检验评估观察者间一致性;以病理结果为金标准,绘制受试者工作特征曲线,计算曲线下面积(AUC),分析Node-RADS评分评估乳腺癌腋窝淋巴结转移的效能。结果 观察者间Node-RADS评分结果的一致性较好。Node-RADS评分＞2时,2名医师评估乳腺癌腋窝淋巴结转移的AUC最高,分别为0.928及0.921,且其间差异无统计学意义(P＞0.05)。结论 基于DCE-MRI Node-RADS评估乳腺癌腋窝淋巴结转移效能良好;Node-RADS评分＞2高度提示淋巴结转移可能。 |
| 英文摘要: |
| Objective To observe the value of Node-RADS based on dynamic contrast-enhanced MRI (DCE-MRI) for assessing axillary lymph node metastasis of breast cancer. Methods A total of 308 patients with breast cancer were retrospectively enrolled and divided into metastasis group (n=153) and non-metastasis group (n=155) based on the presence of axillary lymph node metastasis or not. Two radiologists independently scored the axillary lymph nodes shown on DCE-MRI according to Node-RADS criteria. Inter-observer scores was assessed using Kappa test. Taken pathological result as the gold standard, receiver operating characteristic curves were plotted, and the area under the curve (AUC) was calculated to evaluate the efficacy of Node-RADS scores for diagnosing axillary lymph node metastasis. Results Good inter-observer consistency of Node-RADS scores was observed. When Node-RADS score＞2, the highest AUC of 2 radiologists was 0.928 and 0.921, respectively, being not significantly different (P＞0.05). Conclusion Node-RADS based on DCE-MRI had good efficacy for evaluating axillary lymph node metastasis of breast cancer. Node-RADS score higher than 2 strongly indicated possibility of lymph node metastasis. |
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