孙明华,彭俪颖,张飞飞,潘玉坤,李童,张继良,谢瑞刚,葛英辉.深度学习全模型迭代算法重建先天性心脏病婴儿胸部低剂量CT图像[J].中国医学影像技术,2025,41(4):525~529
深度学习全模型迭代算法重建先天性心脏病婴儿胸部低剂量CT图像
Artificial intelligence iterative reconstruction for low-dose chest CT images of infants with congenital heart disease
投稿时间:2024-10-18  修订日期:2025-02-20
DOI:10.13929/j.issn.1003-3289.2025.04.004
中文关键词:  婴儿  心脏病  低剂量  体层摄影术,X线计算机  人工智能
英文关键词:infant  heart diseases  low dose  tomography, X-ray computed  artificial intelligence
基金项目:河南省医学科技攻关计划(LHGJ20220123)、先进医用材料与医疗器械全国重点实验室项目(YGSKL-SHTech-2025-KF01)。
作者单位E-mail
孙明华 阜外华中心血管病医院放射科, 上海 201800  
彭俪颖 上海联影医疗科技股份有限公司, 上海 201800  
张飞飞 阜外华中心血管病医院放射科, 上海 201800  
潘玉坤 阜外华中心血管病医院放射科, 上海 201800  
李童 阜外华中心血管病医院放射科, 上海 201800  
张继良 阜外华中心血管病医院放射科, 上海 201800  
谢瑞刚 阜外华中心血管病医院放射科, 上海 201800  
葛英辉 阜外华中心血管病医院放射科, 上海 201800
河南省心脏病影像医学重点实验室, 河南 郑州 451460 
cjr.geyinghui@vip.163.com 
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中文摘要:
      目的 观察深度学习全模型迭代算法(AIIR)用于重建先天性心脏病婴儿胸部低剂量CT图像的价值。方法 前瞻性纳入262例拟接受胸部CT检查的先天性心脏病婴儿,随机将其分为低剂量组(n=142)与常规剂量组(n=120)。对低剂量组以管电压80 kVp、管电流10 mAs行胸部CT扫描,分别采用混合迭代重建(HIR,A组)和AIIR(B组)重建图像;对常规剂量组以管电压80 kVp、管电流100 mAs行胸部CT扫描,以HIR重建图像(C组)。比较3组图像主、客观评价结果,分析AIIR的价值。结果 3组图像质量及显示结构清晰度差异均有统计学意义(P均<0.001)。除显示叶间裂清晰度外,B、C组图像主观评分差异均无统计学意义(校正P均>0.05),而A组图像主观评分均低于B、C组(校正P均<0.05)。3组肺实质噪声(SD)、信噪比(SNR)及对比度噪声比(CNR)差异均有统计学意义(P均<0.001),且两两比较差异均有统计学意义(校正P均<0.05)。低剂量组与常规剂量组有效剂量分别为0.09(0.08,0.10)及0.85(0.75,1.03)mSv,前者低于后者(Z=-13.942,P<0.001)。 结论 利用AIIR可使先天性心脏病婴儿胸部低剂量CT图像质量与常规剂量扫描相当。
英文摘要:
      Objective To observe the value of artificial intelligence iterative reconstruction (AIIR) for low-dose chest CT images of infants with congenital heart disease. Methods Totally 262 infants with congenital heart disease who would undergo chest CT scanning were prospectively enrolled and randomly divided into low-dose group (n=142) and conventional dose group (n=120). Chest CT scanning with tube voltage of 80 kVp and tube current of 10 mAs was performed in low-dose group, and hybrid iterative reconstruction (HIR, group A) and AIIR (group B) were used to reconstruct images, respectively. In conventional dose group, chest CT scanning with tube voltage of 80 kVp and tube current of 100 mAs was performed, and HIR was used to reconstruct images (group C). Then subjective and objective evaluation on image quality were performed, the Results were compared among 3 groups, and the value of AIIR was analyzed. Results Significant differences of image quality and clarity of displaying structures were found among 3 groups (all P<0.001). Among them, except for the clarity of interlobar fissure, no significant difference of subjective scores was found between low-dose AIIR images and conventional dose HIR images (all corrected P>0.05), while subjective scores of low-dose HIR images were all lower than those of low-dose AIIR images and conventional dose HIR images (all corrected P<0.05). Significant differences of standard deviation (SD), signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were found among 3 groups (all P<0.001) and between each 2 groups (all corrected P<0.05). The effective dose of low-dose group and conventional dose group was 0.09 (0.08, 0.10) and 0.85 (0.75, 1.03) mSv, respectively, and the former was lower than the latter (Z=-13.942, P<0.001). Conclusion Using AIIR could obtain low-dose chest CT images of infants with quality comparable to conventional chest CT images.
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