| 尹金凤,冯勇,魏学哲,郭君岩,雷明慧,王文娟,刘金刚.合成MRI鉴别宫颈鳞癌与宫颈腺癌[J].中国医学影像技术,2025,41(1):118~121 |
| 合成MRI鉴别宫颈鳞癌与宫颈腺癌 |
| Synthetic MRI for differentiating cervical squamous carcinoma and cervical adenocarcinoma |
| 投稿时间：2024-07-04 修订日期：2024-11-06 |
| DOI：10.13929/j.issn.1003-3289.2025.01.025 |
| 中文关键词: 宫颈肿瘤 肿瘤,组织学类型 诊断,鉴别 多参数磁共振成像 |
| 英文关键词:uterine cervical neoplasms neoplasms by histologic type diagnosis, differential multiparametric magnetic resonance imaging |
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| 中文摘要: |
| 目的 观察合成MRI(SyMRI)MAGiC序列参数鉴别宫颈鳞癌与宫颈腺癌的价值。方法 回顾性纳入66例宫颈癌患者并分为宫颈鳞癌组(n=56)及宫颈腺癌组(n=10),比较组间MAGiC序列定量参数;联合组间存在统计学差异的参数构建logistic回归模型,采用受试者工作特征(ROC)曲线及其曲线下面积(AUC)评估各参数单独及联合鉴别宫颈鳞癌与宫颈腺癌的效能。结果 宫颈腺癌组病变T1、T2均高于而R1、R2均低于宫颈鳞癌组(P均＜0.05);组间质子密度差异无统计学意义(P＞0.05)。单一T1、T2、R1、R2及其联合鉴别宫颈鳞癌与宫颈腺癌ROC曲线的AUC分别为0.959、0.945、0.961、0.942及0.996,两两之间差异均无统计学意义(Z=0.267~1.396,P均＞0.05)。结论 SyMRI鉴别诊断宫颈鳞癌与宫颈腺癌具有较高价值。 |
| 英文摘要: |
| Objective To observe the value of synthetic MRI (SyMRI) MAGnetic resonance image Compilation (MAGiC) sequence parameters for differentiating cervical squamous cell carcinoma and cervical adenocarcinoma. Methods Sixty-six patients with pathologically confirmed cervical cancer were retrospectively enrolled and divided into cervical squamous cell carcinoma group (n=56) and cervical adenocarcinoma group (n=10). Quantitative MAGiC parameters were collected and compared between groups, and those being significantly different were combined to construct a logistic regression model. The performance of each parameter alone and their combination for differentiating cervical squamous cell carcinoma and cervical adenocarcinoma was evaluated with receiver operating characteristic (ROC) curve and the area under the curve (AUC). Results In cervical adenocarcinoma group, lesions's T1 and T2 were higher, while R1 and R2 were lower than those in cervical squamous cell carcinoma group (all P＜0.05). No statistically significant difference of proton density was found between groups (P＞0.05). The AUC of T1, T2, R1, R2 alone and their combination for differentiating cervical squamous cell carcinoma and cervical adenocarcinoma was 0.959, 0.945, 0.961, 0.942 and 0.996, respectively, and no significant difference was found between each two ones (Z=0.267 to 1.396, all P＞0.05). Conclusion SyMRI had high value for differentiating cervical squamous cell carcinoma and cervical adenocarcinoma. |
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